Hydration water rotational motion as a source of configurational entropy driving protein dynamics. Crossovers at 150 and 220 K

被引：49

作者：

Zanotti, J. -M. ^{[1
]}

Gibrat, G. ^{[1
]}

Bellissent-Funel, M. -C. ^{[2
]}

机构：

[1] CEA Saclay, CEA, IRAMIS, Lab Leon Brillouin, F-91191 Gif Sur Yvette, France

[2] CEA Saclay, Lab Le Brillouin, CNRS, F-91191 Gif Sur Yvette, France

来源：

PHYSICAL CHEMISTRY CHEMICAL PHYSICS | 2008年 / 10卷 / 32期

关键词：

D O I：

10.1039/b808217k

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The existence of a protein dynamic transition around 220 K is widely known and the central role of the protein hydration shell is now largely recognized as the driving force for this transition. In this paper, we propose a mechanism, at the molecular level, for the contribution of hydration water. In particular, we identify the key importance of rotational motion of the hydration water as a source of configurational entropy triggering (i) the 220 K protein dynamic crossover (the so-called dynamic transition) but also (ii) a much less intense and scarcely reported protein dynamic crossover, associated to a calorimetric glass transition, at 150 K.

引用

页码：4865 / 4870

页数：6

共 20 条

[1] PROTEIN STATES AND PROTEIN QUAKES [J].

ANSARI, A ;

BERENDZEN, J ;

BOWNE, SF ;

FRAUENFELDER, H ;

IBEN, IET ;

SAUKE, TB ;

SHYAMSUNDER, E ;

YOUNG, RD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (15) :5000-5004

[2] NEUTRON STRUCTURE FACTORS OF INVIVO DEUTERATED AMORPHOUS PROTEIN C-PHYCOCYANIN [J].

BELLISSENTFUNEL, MC ;

LAL, J ;

BRADLEY, KF ;

CHEN, SH .

BIOPHYSICAL JOURNAL, 1993, 64 (05) :1542-1549

[3] Relaxational dynamics of water molecules at protein surface [J].

Dellerue, S ;

Bellissent-Funel, MC .

CHEMICAL PHYSICS, 2000, 258 (2-3) :315-325

[4] The dynamical transition of proteins, concepts and misconceptions [J].

Doster, Wolfgang .

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2008, 37 (05) :591-602

[5] THE PROTEIN-CLASS ANALOGY - SOME INSIGHTS FROM HOMOPEPTIDE COMPARISONS [J].

GREEN, JL ;

FAN, J ;

ANGELL, CA .

JOURNAL OF PHYSICAL CHEMISTRY, 1994, 98 (51) :13780-13790

[6] A POSITRON-ANNIHILATION LIFETIME STUDY OF PROTEIN HYDRATION - EVIDENCE FOR A GLASS-TRANSITION [J].

GREGORY, RB ;

CHAI, KJ .

JOURNAL DE PHYSIQUE IV, 1993, 3 (C4) :305-310

[7] Harmonicity in slow protein dynamics [J].

Hinsen, K ;

Petrescu, AJ ;

Dellerue, S ;

Bellissent-Funel, MC ;

Kneller, GR .

CHEMICAL PHYSICS, 2000, 261 (1-2) :25-37

[8] Role of the solvent in the dynamical transitions of proteins: The case of the lysozyme-water system [J].

Mallamace, Francesco ;

Chen, Sow-Hsin ;

Broccio, Matteo ;

Corsaro, Carmelo ;

Crupi, Vincenza ;

Majolino, Domenico ;

Venuti, Valentina ;

Baglioni, Piero ;

Fratini, Emiliano ;

Vannucci, Chiara ;

Stanley, H. Eugene .

JOURNAL OF CHEMICAL PHYSICS, 2007, 127 (04)

[9] Low-temperature heat capacity and glassy behavior of lysozyme crystal [J].

Miyazaki, Y ;

Matsuo, T ;

Suga, H .

JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (33) :8044-8052

[10] Conductivity in hydrated proteins: No signs of the fragile-to-strong crossover [J].

Pawlus, S. ;

Khodadadi, S. ;

Sokolov, A. P. .

PHYSICAL REVIEW LETTERS, 2008, 100 (10)

← 1 2 →