Reactivity to dietary gluten: new insights into differential diagnosis among gluten-related gastrointestinal disorders

被引：9
作者：
Picarelli, Antonio [1 ]
Borghini, Raffaele [1 ]
Isonne, Claudia [1 ]
Di Tola, Marco [1 ]
机构：
[1] Univ Roma La Sapienza, Dept Internal Med & Med Specialties, Ctr Res & Study Celiac Dis, I-00161 Rome, Italy
来源：
POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE | 2013年 / 123卷 / 12期
关键词：
celiac disease; nonceliac gluten sensitivity; organ culture; wheat allergy; ANTITISSUE TRANSGLUTAMINASE ANTIBODIES; CELIAC-DISEASE DIAGNOSIS; ORGAN-CULTURE SYSTEM; SELECTIVE IGA DEFICIENCY; BASOPHIL ACTIVATION TEST; VITRO GLIADIN CHALLENGE; ENDOMYSIAL ANTIBODIES; PEPTIDE ANTIBODIES; MULTICENTER; SENSITIVITY;
D O I：
10.20452/pamw.2019
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The ingestion of dietary gluten sometimes may trigger allergic, autoimmune or nonallergic and nonautoimmune response. The typical gluten-related allergic disorder is the wheat allergy (WA). Celiac disease (CD) is a well-known gluten-related autoimmune condition. The clinical expression of a gluten-related nonallergic and nonautoimmune response is nonceliac gluten sensitivity (NCGS), an emerging condition whose framework is yet unclear and whose diagnosis is suggested only by demonstration of gluten-dependency in patient' symptoms after exclusion of WA and CD. This review discusses the current tools to identify patients suffering from WA, CD, and NCGS, as well as the most recent insights in the differential diagnosis among these gluten-related gastrointestinal disorders
引用
收藏
页码：708 / 712
页数：5
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