Curing Baldness Activates Antibiotic Production

被引：9
作者：
Chater, Keith F. [1 ]
机构：
[1] John Innes Ctr Plant Sci Res, Norwich NR4 7UH, Norfolk, England
来源：
CHEMISTRY & BIOLOGY | 2013年 / 20卷 / 10期
关键词：
STREPTOMYCES-COELICOLOR; GENES; CODON; BLDA;
D O I：
10.1016/j.chembiol.2013.10.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Kalan and colleagues describe an unusual way of activating a "silent" gene cluster for the biosynthesis of a new antibiotic by analyzing and curing the aerial growth defect of an old Streptomyces isolate, Streptomyces calvus. This commentary addresses the broad scientific and historical context and practical and biological significance of this finding.
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收藏
页码：1199 / 1200
页数：2
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