Type II Diabetes Mellitus - Associated Risk Factor in the Onset and Evolution of Digestive Tract Carcinoma

Introduction: The number of digestive cancers cases has alarmingly increased within the past decades up to a current third place ranking in terms of global incidence. The association between type II diabetes mellitus and digestive neoplasms has been on an upward trend lately due to common risk factors as well as to mutually potentiating effects on the evolution of the two conditions. Patients and methods: This clinical study evaluates a group of 34 gastro intestinal cancer patients suffering from type II diabetes mellitus who received treatment in 'Elias University Emergency Hospital', Medical Oncology division, between 2010 and 2016. A number of demographic features specific to the aforementioned group, as well as comorbidities linked to localization, the aggressiveness of primary digestive tumor and the presence of the biological inflammatory syndrome were evaluated. Discussion: Digestive neoplasms associated with type II diabetes mellitus turn out to be more aggressive. The therapy is burdened by potential risks arising from all associated pathologies. Conclusions: A set of clinical and biological data underpin the association between type II diabetes mellitus and digestive neoplasms as being detrimental. Therefore, screening measures for digestive neoplasms in type II diabetes mellitus patients should be carefully respected.