PVA/PAA-Based Antibacterial Wound Dressing Material with Aloe Vera

被引:27
|
作者
Serincay, Halime [1 ]
Ozkan, Semiha [2 ]
Yilmaz, Nurdane [3 ]
Kocyigit, Serhat [1 ,4 ]
Uslu, Ibrahim [5 ,6 ]
Gurcan, Safa [7 ]
Arisoy, Mustafa [8 ]
机构
[1] Gazi Univ, Inst Sci, Dept Adv Technol, TR-06500 Ankara, Turkey
[2] Gazi Univ, Fac Pharm, Ankara, Turkey
[3] Ankara Univ, Fac Sci, Dept Chem, TR-06100 Ankara, Turkey
[4] Aksaray Univ, Fac Educ, Dept Sci Educ, Aksaray, Turkey
[5] Gazi Univ, Fac Educ, Dept Chem Educ, Ankara, Turkey
[6] Gazi Univ, Fac Educ, Dept Chem Educ, Ankara, Turkey
[7] Ankara Univ, Fac Vet, TR-06100 Ankara, Turkey
[8] Ankara Univ, Fac Pharm, Dept Pharmaceut Chem, TR-06100 Ankara, Turkey
关键词
Aloe vera; Ciprofloxacin HCL; Nanofiber; Wound dressing; POLY(VINYL ALCOHOL); ELECTROSPUN NANOFIBERS; CROSS-LINKING; MICROSPHERES; IMPROVEMENT; HYDROGEL; RELEASE; POLYMER; WATER; MATS;
D O I
10.1080/03602559.2013.814671
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
The incorporation of drugs into the dressings make these dressings antimicrobial and help in control of infection around the wound. The wound dressing materials based on PVA/PAA, ciprofloxacin HCl, and aloe vera have been designed and developed so that the wound undergoes proper healing and scar formation is minimal. These wound dressing materials are produced using the electrospinning method. The wound dressing materials are characterized using the FT-IR, DSC, DTA, TGA, and SEM techniques. The wound dressing materials are tested for microbial activity tests and drug release experiments. Controlled ciprofloxacin HCl release is observed.
引用
收藏
页码:1308 / 1315
页数:8
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