Cardiac dysfunction and N-terminal pro-B-type natriuretic peptide in exacerbations of chronic obstructive pulmonary disease

被引：17

作者：

Lee, M. H. S. ^{[1
,2
]}

Chang, C. L. ^{[1
]}

Davies, A. R. ^{[1
]}

Davis, M. ^{[2
]}

Hancox, R. J. ^{[1
,3
]}

机构：

[1] Waikato Hosp, Resp Res Unit, Dept Resp Med, Hamilton, New Zealand

[2] Waikato Hosp, Dept Cardiol, Hamilton, New Zealand

[3] Univ Otago, Dept Prevent & Social Med, Dunedin, New Zealand

来源：

INTERNAL MEDICINE JOURNAL | 2013年 / 43卷 / 05期

关键词：

COPD; heart failure; BNP; NT-proBNP; echocardiography; TAPSE; ECHOCARDIOGRAPHIC-ASSESSMENT; VENTRICULAR DYSFUNCTION; COR-PULMONALE; COPD; MORTALITY; HEART;

D O I：

10.1111/imj.12112

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Elevated levels of B-type natriuretic peptides among patients with exacerbations of chronic obstructive pulmonary disease (COPD) are associated with higher mortality. The pathophysiology is unclear. To establish if elevated levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) are due to right or left heart dysfunction, we performed echocardiograms in 18 patients admitted to hospital with COPD. Elevated levels of NT-proBNP were associated with both right and left heart dysfunction and indicate that these patients have biventricular dysfunction rather than isolated right ventricular compromise.

引用

页码：595 / 598

页数：4

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