Towards an Efficient Preparation of Hydromorphone

被引：7

作者：

Csuk, Rene ^{[1
]}

Vasileva, Galina ^{[1
]}

Barthel, Alexander ^{[1
]}

机构：

[1] Univ Halle Wittenberg, Bereich Organ Chem, D-06120 Halle, Saale, Germany

来源：

SYNTHESIS-STUTTGART | 2012年 / 44卷 / 18期

关键词：

alkaloids; catalysis; oxidation; reduction; supported catalysis; MORPHINE ALKALOIDS; TRANSFORMATIONS; HYDROGENATION; GRAPHITE;

D O I：

10.1055/s-0031-1291151

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dihydromorphone was prepared from morphine in high yield, excellent purity, and low residual metal content. The key steps used palladium on porous glass and a modified Oppenauer oxidation, or Wilkinson's catalyst.

引用

页码：2840 / 2842

页数：3

共 35 条

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