Towards an Efficient Preparation of Hydromorphone

被引：7
作者：
Csuk, Rene [1 ]
Vasileva, Galina [1 ]
Barthel, Alexander [1 ]
机构：
[1] Univ Halle Wittenberg, Bereich Organ Chem, D-06120 Halle, Saale, Germany
来源：
SYNTHESIS-STUTTGART | 2012年 / 44卷 / 18期
关键词：
alkaloids; catalysis; oxidation; reduction; supported catalysis; MORPHINE ALKALOIDS; TRANSFORMATIONS; HYDROGENATION; GRAPHITE;
D O I：
10.1055/s-0031-1291151
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Dihydromorphone was prepared from morphine in high yield, excellent purity, and low residual metal content. The key steps used palladium on porous glass and a modified Oppenauer oxidation, or Wilkinson's catalyst.
引用
收藏
页码：2840 / 2842
页数：3
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