Role of 5′AMP-activated protein kinase in skeletal muscle

被引：6
|
作者：
Treebak, J. T. [1 ]
Wojtaszewski, J. F. P. [1 ]
机构：
[1] Univ Copenhagen, Mol Physiol Grp, Copenhagen Muscle Res Ctr, Inst Exercise & Sport Sci, DK-2100 Copenhagen, Denmark
来源：
INTERNATIONAL JOURNAL OF OBESITY | 2008年 / 32卷 / Suppl 4期
关键词：
AMPK; contraction; exercise; energy balance; insulin sensitivity;
D O I：
10.1038/ijo.2008.117
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
5'AMP-activated protein kinase (AMPK) is recognized as an important intracellular energy sensor, shutting down energy-consuming processes and turning on energy-generating processes. Discovery of target proteins of AMPK has dramatically increased in the past 10 years. Historically, AMPK was first shown to regulate fatty acid and cholesterol synthesis, but is now hypothesized to take part in the regulation of energy/fuel balance not only at the cellular level but also at the level of the whole organism. In this brief review we will discuss some of the roles of AMPK in skeletal muscle.
引用
收藏
页码：S13 / S17
页数：5
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