Neuromuscular Electrical Stimulation during Hemodialysis Suppresses Postprandial Hyperglycemia in Patients with End-Stage Diabetic Kidney Disease: A Crossover Controlled Trial

被引:3
作者
Tsurumi, Tomoki [1 ]
Tamura, Yuma [1 ]
Nakatani, Yuki [2 ]
Furuya, Tomoki [3 ,4 ,5 ]
Tamiya, Hajime [3 ,6 ]
Terashima, Masato [1 ]
Tomoe, Takashi [3 ]
Ueno, Asuka [3 ]
Shimoyama, Masahiro [3 ]
Yasu, Takanori [3 ]
机构
[1] Dokkyo Med Univ, Nikko Med Ctr, Dept Rehabil, Nikko 3212593, Japan
[2] Dokkyo Med Univ, Nikko Med Ctr, Dept Diabet & Endocrinol, Nikko 3212593, Japan
[3] Dokkyo Med Univ, Nikko Med Ctr, Dept Cardiovasc Med & Nephrol, Nikko 3212593, Japan
[4] Tokyo Metropolitan Inst Gerontol, Social Participat & Community Hlth Res Team, Tokyo, Tokyo 1730015, Japan
[5] Igaku Acad, Dept Phys Therapy, Kawagoe, Saitama 3500003, Japan
[6] Niigata Univ Hlth & Welf, Inst Human Movement & Med Sci, Niigata 9503198, Japan
关键词
diabetic kidney disease; neuromuscular electrical stimulation; glycemic control; hemodialysis; MUSCLE STRENGTH; GLYCEMIC VARIABILITY; FUNCTIONAL-CAPACITY; GLUCOSE; SARCOPENIA;
D O I
10.3390/jcm11216239
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hemodialysis patients with diabetic kidney disease (DKD) experience blood glucose fluctuations owing to insulin removal. We evaluated the effects of single and long-term application of neuromuscular electrical stimulation (NMES) during hemodialysis on glycemic control. This trial was conducted in two stages: Stage 1, following a crossover design and 4 week washout period, eleven outpatients with DKD either underwent a single bout of NMES for 30 min (NMES period) or rested (control period) after receiving nutritional support during hemodialysis; Stage 2, following a crossover design and 4 week washout period, each participant received the intervention for 12 weeks. NMES was administered for 30 min at the maximum tolerable intensity. The mean subcutaneous glucose concentration and mean amplitude of glycemic excursion (MAGE) were determined by flash glucose monitoring for 24 h. Changes in glycoalbumin and MAGE before and after NMES initiation were evaluated. The mean blood glucose level and MAGE after a single bout of NMES were significantly lower than those after rest. Glycoalbumin levels and echo intensity of the rectus femoris tended to decrease, but not significantly by ANOVA due to a lack in statistical power after the dropout of three patients. NMES in end-stage DKD decreased blood glucose levels during and after hemodialysis.
引用
收藏
页数:11
相关论文
共 29 条
  • [1] Evaluation of the hemodialysis-induced changes in plasma glucose and insulin concentrations in diabetic patients: Comparison between the hemodialysis and non-hemodialysis days
    Abe, Masanori
    Kaizu, Kazo
    Matsumoto, Koichi
    [J]. THERAPEUTIC APHERESIS AND DIALYSIS, 2007, 11 (04) : 288 - 295
  • [2] Andersen E, 2007, J STRENGTH COND RES, V21, P487
  • [3] A Novel Amino Acids Oral Supplementation in Hemodialysis Patients: a Pilot Study
    Bolasco, Piergiorgio
    Caria, Stefania
    Cupisti, Adamasco
    Secci, Romina
    Dioguardi, Francesco Saverio
    [J]. RENAL FAILURE, 2011, 33 (01) : 1 - 5
  • [4] Global Prevalence of Protein-Energy Wasting in Kidney Disease: A Meta-analysis of Contemporary Observational Studies From the International Society of Renal Nutrition and Metabolism
    Carrero, Juan J.
    Thomas, Fridtjof
    Nagy, Kristof
    Arogundade, Fatiu
    Avesani, Carla M.
    Chan, Maria
    Chmielewski, Michal
    Cordeiro, Antottio C.
    Espinosa-Cuevas, Angeles
    Fiaccadori, Enrico
    Guebre-Egziabher, Fitsum
    Hand, Rosa K.
    Hung, Adriana M.
    Ikizler, Talat A.
    Johansson, Lina R.
    Kalantar-Zadeh, Kamyar
    Karupaiah, Tilakavati
    Lindholm, Bengt
    Marckmann, Peter
    Mafra, Denise
    Parekh, Rulan S.
    Park, Jongha
    Russo, Sharon
    Saxena, Anita
    Sezer, Siren
    Teta, Daniel
    Ter Wee, Pieter M.
    Verseput, Cecile
    Wang, Angela Y. M.
    Xu, Hong
    Lu, Yimin
    Molnar, Miklos Z.
    Kovesdy, Csaba P.
    [J]. JOURNAL OF RENAL NUTRITION, 2018, 28 (06) : 380 - 392
  • [5] Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment
    Chen, Liang-Kung
    Woo, Jean
    Assantachai, Prasert
    Auyeung, Tung-Wai
    Chou, Ming-Yueh
    Iijima, Katsuya
    Jang, Hak Chul
    Kang, Lin
    Kim, Miji
    Kim, Sunyoung
    Kojima, Taro
    Kuzuya, Masafumi
    Lee, Jenny S. W.
    Lee, Sang Yoon
    Lee, Wei-Ju
    Lee, Yunhwan
    Liang, Chih-Kuang
    Lim, Jae-Young
    Lim, Wee Shiong
    Peng, Li-Ning
    Sugimoto, Ken
    Tanaka, Tomoki
    Won, Chang Won
    Yamada, Minoru
    Zhang, Teimei
    Akishita, Masahiro
    Arai, Hidenori
    [J]. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2020, 21 (03) : 300 - +
  • [6] The contribution of chronic kidney disease to the global burden of major noncommunicable diseases
    Couser, William G.
    Remuzzi, Giuseppe
    Mendis, Shanthi
    Tonelli, Marcello
    [J]. KIDNEY INTERNATIONAL, 2011, 80 (12) : 1258 - 1270
  • [7] The effect of neuromuscular electrical stimulation on muscle strength, functional capacity and body composition in haemodialysis patients
    Esteve, Vicent
    Carneiro, Jose
    Moreno, Fatima
    Fulquet, Miguel
    Garriga, Salud
    Pou, Monica
    Duarte, Veronica
    Saurina, Anna
    Tapia, Irati
    de Arellano, Manel Ramirez
    [J]. NEFROLOGIA, 2017, 37 (01): : 68 - 77
  • [8] Uraemic sarcopenia: aetiology and implications
    Fahal, Ibrahim H.
    [J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2014, 29 (09) : 1655 - 1665
  • [9] A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease
    Fouque, D.
    Kalantar-Zadeh, K.
    Kopple, J.
    Cano, N.
    Chauveau, P.
    Cuppari, L.
    Franch, H.
    Guarnieri, G.
    Ikizler, T. A.
    Kaysen, G.
    Lindholm, B.
    Massy, Z.
    Mitch, W.
    Pineda, E.
    Stenvinkel, P.
    Trevinho-Becerra, A.
    Wanner, C.
    [J]. KIDNEY INTERNATIONAL, 2008, 73 (04) : 391 - 398
  • [10] Biochemical evidence of cell starvation in diabetic hemodialysis patients
    Fujiwara, Masako
    Ando, Itiro
    Satoh, Keisuke
    Shishido, You
    Totsune, Kazuhito
    Sato, Hiroshi
    Imai, Yutaka
    [J]. PLOS ONE, 2018, 13 (09):