Decarboxylative Biaryl Synthesis from Aromatic Carboxylates and Aryl Triflates

被引：230

作者：

Goossen, Lukas J. ^{[1
]}

Rodriguez, Nuria ^{[1
]}

Linder, Christophe ^{[1
]}

机构：

[1] TU Kaiserslautern, FB Chem Organ Chem, D-67663 Kaiserslautern, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 46期

关键词：

D O I：

10.1021/ja8050926

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new catalyst system, generated in situ from Cu2O, 1,10-phenanthroline, Pdl(2), and Tol-BINAP, for the first time allows the decarboxylative coupling of carboxylic acids with aryl triflates. In contrast to previous decarboxylative couplings that remained limited to certain activated carboxytates, e.g., ortho-substituted benzoates, this halide-free protocol is generally applicable to aromatic carboxylic acid salts regardless of their substitution pattern.

引用

页码：15248 / +

页数：3

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