More on target with protein phosphorylation: Conferring specificity by location

被引:131
作者
Faux, MC
Scott, JD
机构
关键词
D O I
10.1016/S0968-0004(96)10040-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
One important regulatory mechanism in the control of phosphorylation events is the subcellular location of phosphatases or kinases. Several serine/threonine phosphatases and kinases have now been shown to be associated with targeting subunits; these contribute to the organization and specificity of signal transduction pathways by favoring the accessibility of their enzymes to certain substrates.
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页码:312 / 315
页数:4
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