Magnetic Two-Way Valves for Paper-Based Capillary-Driven Microfluidic Devices

被引：45

作者：

Fratzl, Mario ^{[1
,2
]}

Chang, Boyce S. ^{[3
]}

Oyola-Reynoso, Stephanie ^{[3
]}

Blaire, Guillaume ^{[1
]}

Delshadi, Sarah ^{[1
,5
,6
]}

Devillers, Thibaut ^{[2
]}

Ward, Thomas, III ^{[4
]}

Dempsey, Nora M. ^{[2
]}

Bloch, Jean-Francis ^{[7
]}

Thuo, Martin M. ^{[3
]}

机构：

[1] Univ Grenoble Alpes, CNRS, Grenoble INP, Inst Engn,G2Elab, F-38000 Grenoble, France

[2] Univ Grenoble Alpes, CNRS, Inst Engn, Grenoble INP,Inst Neel, F-38000 Grenoble, France

[3] Iowa State Univ, Dept Mat Sci & Engn, Ames, IA 50011 USA

[4] Iowa State Univ, Dept Aerosp Engn, Ames, IA 50011 USA

[5] Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France

[6] Site Sante,Allee Alpes, F-38700 La Tronche, France

[7] Univ Grenoble Alpes, CNRS, Grenoble INP, Inst Engn,3SR, F-38000 Grenoble, France

来源：

ACS OMEGA | 2018年 / 3卷 / 02期

关键词：

CARE DIAGNOSTIC DEVICES; NETWORK FORMAT; LAYERED PAPER; FLUID CONTROL; FABRICATION; FLOW; SENSORS; ASSAY;

D O I：

10.1021/acsomega.7b01839

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This article presents a magnetically actuated two-way, three-position (+, 0, -), paper-based microfluidic valve that includes a neutral position (0). the first of its kind. The system is highly robust, customizable, and fully automated. The advent of a neutral position and the ability to precisely control switching frequencies establish a new platform for highly controlled fluid flows in paper-based wicking microfluidic devices. The potential utility of these valves is demonstrated in automated, programmed, patterning of dyed liquids in a wicking device akin to a colorimetric assay but with a programmed fluid/reagent delivery. These valves are fabricated using facile methods and thus remain cost-effective for adoption into affordable point-of-care/bioanalytical devices.

引用

页码：2049 / 2057

页数：9

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