Identification of a NK-1R Antagonist as a Novel Therapeutic Approach in Colon Cancer by High Throughput Chemical Screening

被引:0
|
作者
Polytarchou, Christos
Palumbo, Tiziana
Bugni, James M.
Pothoulakis, Charalabos
Iliopoulos, Dimitrios
机构
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:S117 / S118
页数:2
相关论文
共 50 条
  • [41] High-throughput screening identified pacritinib as a promising therapeutic approach to overcome lenvatinib resistance in hepatocellular carcinoma by targeting IRAK1
    Li, Changyu
    Chen, Xiaoyu
    Wu, Jianghao
    Heng, Shan
    Xu, Zihao
    Gu, Hongyi
    Lin, Enhua
    Wang, Jiazhen
    Shan, Yunfeng
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 734
  • [42] Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ-TEAD Biosensors
    Nouri, Kazem
    Azad, Taha
    Ling, Min
    van Rensburg, Helena J. Janse
    Pipchuk, Alexander
    Shen, He
    Hao, Yawei
    Zhang, Jianmin
    Yang, Xiaolong
    CANCERS, 2019, 11 (10)
  • [43] Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
    Liang, Xuewu
    Sun, Chenxia
    Li, Chunpu
    Yu, Haolan
    Wei, Xiaohui
    Liu, Xuyi
    Bao, Wei
    Shi, Yuqiang
    Sun, Xiaochen
    Khamrakulov, Mirzadavlat
    Yang, Chenghua
    Liu, Hong
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (13) : 9217 - 9237
  • [44] Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics
    Zhang, Wen
    Hu, Xiaohui
    Chakravarty, Harapriya
    Yang, Zheng
    Tam, Kin Yip
    ACS COMBINATORIAL SCIENCE, 2018, 20 (11) : 660 - 671
  • [45] High-throughput drug screening (HTDS) of patient-derived tumor organoids (PTDO) from advanced gastrointestinal malignancies: Response and identification of novel therapeutic options
    Khan, Uqba
    Us, Ilkay
    Moyer, Jenna
    Kasi, Pashtoon Murtaza
    Ocean, Allyson J.
    Podaza, Enrique
    Sarkar, Sandipto
    Savenkov, Oleksandr
    Martin, M. Laura
    Shah, Manish A.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [46] Novel approach for GPCR drug discovery: Indirect identification of S1P receptor agonists in antagonist screening using calcium measurements.
    Siehler, Sandra
    Guerini, Danilo
    ACTA PHARMACOLOGICA SINICA, 2006, 27 : 247 - 247
  • [47] Identification of Wee1 and IGF-1R As Novel Therapeutic Targets for Mutant RAS-Driven Acute Leukemia By Combinatory Chemical Screens
    Nonami, Atsushi
    Zhao, Chen
    Liu Qingsong
    Cowens, Kristen
    Christie, Amanda L.
    Chen, Yongfei
    Sattler, Martin
    Wang, Kwok-Kin
    Gray, Nathanael S.
    Griffin, James D.
    Weisberg, Ellen L.
    BLOOD, 2014, 124 (21)
  • [48] Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening
    Thomas, David R.
    Lundberg, Lindsay
    Pinkham, Chelsea
    Shechter, Sharon
    DeBono, Aaron
    Baell, Jonathan
    Wagstaff, Kylie M.
    Hick, Caroline A.
    Kehn-Hall, Kylene
    Jans, David A.
    ANTIVIRAL RESEARCH, 2018, 151 : 8 - 19
  • [49] Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform
    Murai, Junko
    Marchand, Christophe
    Shahane, Sampada A.
    Sun, Hongmao
    Huang, Ruili
    Zhang, Yiping
    Chergui, Adel
    Ji, Jiuping
    Doroshow, James H.
    Jadhav, Ajit
    Takeda, Shunichi
    Xia, Menghang
    Pommier, Yves
    DNA REPAIR, 2014, 21 : 177 - 182
  • [50] Identification of Notch1 downstream effectors as novel drug targets in multiple myeloma by shRNA-based high-throughput functional screening
    Maichl, D. S.
    Ziouti, F.
    Schmidt, S.
    Ade, C. P.
    Eilers, M.
    Jundt, F.
    ONCOLOGY RESEARCH AND TREATMENT, 2018, 41 : 193 - 193