A covariance-based test for shared frailty in multivariate lifetime data

被引:0
|
作者
Kimber, Alan [1 ,2 ]
Sarker, Shah-Jalal [3 ]
机构
[1] Univ Southampton, Sch Math, Southampton, Hants, England
[2] Univ Southampton, Southampton Stat Sci Res Inst, Southampton, Hants, England
[3] Queen Mary Univ London, Ctr Expt Canc Med, Barts Canc Inst, London, England
关键词
shared frailty; finite variance frailty; multivariate lifetimes; Weibull distribution; proportional hazards; score statistic; ESTIMATORS; MODELS;
D O I
10.1080/02664763.2012.720966
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We decompose the score statistic for testing for shared finite variance frailty in multivariate lifetime data into marginal and covariance-based terms. The null properties of the covariance-based statistic are derived in the context of parametric lifetime models. Its non-null properties are estimated using simulation and compared with those of the score test and two likelihood ratio tests when the underlying lifetime distribution is Weibull. Some examples are used to illustrate the covariance-based test. A case is made for using the covariance-based statistic as a simple diagnostic procedure for shared frailty in a parametric exploratory analysis of multivariate lifetime data and a link to the bivariate Clayton-Oakes copula model is shown.
引用
收藏
页码:2509 / 2522
页数:14
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