Synthesis and NMR spectral assignments of novel nitrogen and sulfur heterocyclic compounds

被引：12

作者：

Chandrashekhar, N. ^{[2
,3
]}

Thomas, Bejoy ^{[1
]}

Gayathri, V. ^{[2
]}

Ramanathan, K. V. ^{[1
]}

Gowda, N. M. Nanje ^{[2
]}

机构：

[1] Bangalore Univ, Indian Inst Sci, NMR Res Ctr, Bangalore 560001, Karnataka, India

[2] Bangalore Univ, Dept Studies Chem, Bangalore 560001, Karnataka, India

[3] Bruker India Sci Pvt Ltd, Bangalore 560012, Karnataka, India

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2008年 / 46卷 / 08期

关键词：

H-1; NMR; C-13{H-1} NMR; 2D NMR; 1D NOE experiment; N and S heterocycles;

D O I：

10.1002/mrc.2239

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis and NMR spectral studies of multidentate N and S heterocycles, 1,3,5-tris(N-methylbenzimidazolyl)benzene, 1,3,5-tris(benzimidazolyl)benzene,1,3,5-tris(benzothiazolyi) benzene, 2,2'-bipyridine 3,3'-bis(benzoth iazolyl) benzene and 1,2,4,5-tetrakis(benzothiazolyl) benzene have been carried out. 2D H-1-H-1 PFG-COSY as well as H-1-C-13 single and multiple bond correlated (2D GRASP-HSQC and GRASP-HMBC) experiments have been employed to characterize the compounds. 1D NOE experiments have been useful in understanding the structure of 1,3,5-tris(N-methylenzimidazolyl) benzene. Copyright (C) 2008 John Wiley & Sons, Ltd.

引用

收藏

页码：769 / 774

页数：6

相关论文

共 28 条

[1] SYNTHESIS OF FUSED RING HETEROCYCLES FROM AROMATIC-AMINES WITH HYDROXIMOYL CHLORIDES [J].

ABDELHAMID, AO ;

PARKANYI, C ;

RASHID, SMK ;

LLOYD, WD .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (02) :403-405

[2] H-1 AND C-13 ASSIGNMENTS FROM SENSITIVITY-ENHANCED DETECTION OF HETERONUCLEAR MULTIPLE-BOND CONNECTIVITY BY 2D MULTIPLE QUANTUM NMR [J].

BAX, A ;

SUMMERS, MF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (08) :2093-2094

[3] 1H and 13C chemical shifts for 2-aryl and 2-N-arylamino benzothiazole derivatives [J].

Billeau, S ;

Chatel, F ;

Robin, M ;

Faure, R ;

Galy, JP .

MAGNETIC RESONANCE IN CHEMISTRY, 2006, 44 (01) :102-105

[4] A C-13 NUCLEAR MAGNETIC-RESONANCE STUDY OF A SERIES OF 5-SUBSTITUTED BENZIMIDAZOLES [J].

BLACKBURN, BJ ;

ANKROM, DW ;

HUTTON, HM .

CANADIAN JOURNAL OF CHEMISTRY, 1982, 60 (24) :2987-2992

[5] The antitumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces NF-κB activity in drug-sensitive MCF-7 cells [J].

Brantley, E ;

Patel, V ;

Stinson, SF ;

Trapani, V ;

Hose, CD ;

Ciolino, HP ;

Yeh, GC ;

Gutkind, JS ;

Sausville, EA ;

Loaiza-Pérez, AI .

ANTI-CANCER DRUGS, 2005, 16 (02) :137-143

[6]

Cavanagh J., 1993, Annu. Rep. NMR Spectrosc, V27, P1

[7] Synthesis and antileishmanial activity of (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives [J].

Delmas, F ;

Avellaneda, A ;

Di Giorgio, C ;

Robin, M ;

De Clercq, E ;

Timon-David, P ;

Galy, JP .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2004, 39 (08) :685-690

[8] C-13-NMR STUDY OF POLYHETEROATOMIC 5-RING HETEROCYCLES - EFFECT OF SUBSTITUENT, OF BENZO CONDENSATION, AND STUDY OF PROTOTROPIC TAUTOMERISM IN BENZOTHIAZOLO SERIES [J].

FAURE, R ;

ELGUERO, J ;

VINCENT, EJ ;

LAZARO, R .

ORGANIC MAGNETIC RESONANCE, 1978, 11 (12) :617-627

[9] BENZOFUROBENZTHIAZOLE .6. H-1 AND C-13 NMR-SPECTRA OF "2-AMINOBENZOFURO[2,3-F]BENZTHIAZOLE AND "2-AMINOBENZOFURO[2,3-E]BENZTHIAZOLE COMPARED WITH THOSE OF DIBENZOFURAN AND 2-AMINOBENZTHIAZOLE [J].

FLOREA, S ;

KIMPENHAUS, W .

ORGANIC MAGNETIC RESONANCE, 1977, 9 (03) :133-140

[10] Cyclometallation of bis-benzimidazole derivatives with rhodium(III) halides [J].

Gayathri, V ;

Leelamani, EG ;

Gowda, NMN ;

Reddy, GKN .

POLYHEDRON, 1999, 18 (18) :2351-2360