Tocilizumab not associated with increased infection risk after CAR T-cell therapy: implications for COVID-19?

被引：60

作者：

Frigault, Matthew J. ^{[1
]}

Nikiforow, Sarah ^{[2
]}

Mansour, Michael K. ^{[3
]}

Hu, Zhen-Huan ^{[4
]}

Horowitz, Mary M. ^{[4
,5
]}

Riches, Marcie L. ^{[6
]}

Hematti, Peiman ^{[7
]}

Turtle, Cameron J. ^{[8
]}

Zhang, Mei-Jie ^{[4
]}

Perales, Miguel-Angel ^{[9
]}

Pasquini, Marcelo C. ^{[4
,5
]}

机构：

[1] Massachusetts Gen Hosp, Cellular Immunotherapy Program, Boston, MA 02114 USA

[2] Dana Farber Canc Inst, Dept Med, Div Hematol Malignancies, Boston, MA 02115 USA

[3] Massachusetts Gen Hosp, Dept Med, Div Infect Dis, Boston, MA 02114 USA

[4] Med Coll Wisconsin, Ctr Int Blood & Marrow Transplant Res, 9200 West Wisconsin Ave, Milwaukee, WI 53226 USA

[5] Med Coll Wisconsin, Blood & Marrow Transplant & Cellular Therapy Prog, Milwaukee, WI 53226 USA

[6] Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC 27515 USA

[7] Univ Wisconsin, Dept Med, Div Hematol Oncol Bone Marrow Transplantat, Madison, WI USA

[8] Univ Washington, Dept Med, Seattle, WA USA

[9] Mem Sloan Kettering Canc Ctr, Adult Blood & Marrow Transplant Serv, 1275 York Ave, New York, NY 10021 USA

来源：

BLOOD | 2020年 / 136卷 / 01期

基金：

美国国家卫生研究院;

关键词：

CYTOKINE RELEASE SYNDROME;

D O I：

10.1182/blood.2020006216

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：137 / 139

页数：3

共 21 条

[1] Covid-19 in Critically Ill Patients in the Seattle Region - Case Series
Bhatraju, Pavan K.
Ghassemieh, Bijan J.
Nichols, Michelle
Kim, Richard
Jerome, Keith R.
Nalla, Arun K.
Greninger, Alexander L.
Pipavath, Sudhakar
Wurfel, Mark M.
Evans, Laura
Kritek, Patricia A.
West, T. Eoin
Luks, Andrew
Gerbino, Anthony
Dale, Chris R.
Goldman, Jason D.
O'Mahony, Shane
Mikacenic, Carmen
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (21) : 2012 - 2022
[2] Center for International Blood and Marrow Transplant Research, CELL IMM DAT RES CID
[3] Clinical and immunological features of severe and moderate coronavirus disease 2019
Chen, Guang
Wu, Di
Guo, Wei
Cao, Yong
Huang, Da
Wang, Hongwu
Wang, Tao
Zhang, Xiaoyun
Chen, Huilong
Yu, Haijing
Zhang, Xiaoping
Zhang, Minxia
Wu, Shiji
Song, Jianxin
Chen, Tao
Han, Meifang
Li, Shusheng
Luo, Xiaoping
Zhao, Jianping
Ning, Qin
[J]. JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (05) : 2620 - 2629
[4] Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Chen, Nanshan
Zhou, Min
Dong, Xuan
Qu, Jieming
Gong, Fengyun
Han, Yang
Qiu, Yang
Wang, Jingli
Liu, Ying
Wei, Yuan
Xia, Jia'an
Yu, Ting
Zhang, Xinxin
Zhang, Li
[J]. LANCET, 2020, 395 (10223) : 507 - 513
[5] Tocilizumab added to conventional therapy reverses both the cytokine profile and CD8+Granzyme+ T-cells/NK cells expansion in refractory hemophagocytic lymphohistiocytosis
Faguer, Stanislas
Vergez, Francois
Peres, Michael
Ferrandiz, Ines
Casemayou, Audrey
Belliere, Julie
Cointault, Olivier
Lavayssiere, Laurence
Nogier, Marie-Beatrice
Prevot, Gregoire
Huart, Antoine
Recher, Christian
Rostaing, Lionel
[J]. HEMATOLOGICAL ONCOLOGY, 2016, 34 (01) : 55 - 57
[6] State of the art in CAR T cell therapy for CD19+ B cell malignancies
Frigault, Matthew J.
Maus, Marcela, V
[J]. JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (04) : 1586 - 1594
[7] Why tocilizumab could be an effective treatment for severe COVID-19?
Fu, Binqing
Xu, Xiaoling
Wei, Haiming
[J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 18 (01)
[8] Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial
Locke, Frederick L.
Ghobadi, Armin
Jacobson, Caron A.
Miklos, David B.
Lekakis, Lazaros J.
Oluwole, Olalekan O.
Lin, Yi
Braunschweig, Ira
Hill, Brian T.
Timmerman, John M.
Deol, Abhinav
Reagan, Patrick M.
Stiff, Patrick
Flinn, Ian W.
Farooq, Umar
Goy, Andre
McSweeney, Peter A.
Munoz, Javier
Siddiqi, Tanya
Chavez, Julio C.
Herrera, Alex F.
Bartlett, Nancy L.
Wiezorek, Jeffrey S.
Navale, Lynn
Xue, Allen
Jiang, Yizhou
Bot, Adrian
Rossi, John M.
Kim, Jenny J.
Go, William Y.
Neelapu, Sattva S.
[J]. LANCET ONCOLOGY, 2019, 20 (01) : 31 - 42
[9] Tocilizumab treatment in COVID-19: A single center experience
Luo, Pan
Liu, Yi
Qiu, Lin
Liu, Xiulan
Liu, Dong
Li, Juan
[J]. JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (07) : 814 - 818
[10] Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
Maude, S. L.
Laetsch, T. W.
Buechner, J.
Rives, S.
Boyer, M.
Bittencourt, H.
Bader, P.
Verneris, M. R.
Stefanski, H. E.
Myers, G. D.
Qayed, M.
De Moerloose, B.
Hiramatsu, H.
Schlis, K.
Davis, K. L.
Martin, P. L.
Nemecek, E. R.
Yanik, G. A.
Peters, C.
Baruchel, A.
Boissel, N.
Mechinaud, F.
Balduzzi, A.
Krueger, J.
June, C. H.
Levine, B. L.
Wood, P.
Taran, T.
Leung, M.
Mueller, K. T.
Zhang, Y.
Sen, K.
Lebwohl, D.
Pulsipher, M. A.
Grupp, S. A.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (05) : 439 - 448

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