Preparation of bimodal porous biphasic calcium phosphate ceramics and their dissolution behavior in simulated body fluid

Biphasic calcium phosphate (BCP) ceramics, a mixture of hydroxyapatite (HAp) and beta-tricalcium phosphate (0-TCP), of varying 14Ap/beta-TCP ratios were prepared from fine powders. Porous BCP ceramic materials with HAp/beta-TCP weight rations of 20/80, 40/60, and 80/20 were prepared. In this study, the bioactivity is reduced at a bigger HAp content rate, which is likely related to the high driving pore for the formation of a new phase, and the reaction rate was proportional to the beta-TCP. The porous BCP ceramics having a bigger porosity rate can easily under up dissolution. The powder having a bigger beta-TCP content rate can easily generate a new phase. The dissolution results confirmed that the biodegradation of calcium phosphate ceramics could be controlled by simply adjusting the amount of HAp or beta-TCP in the ceramics and porosity rate.