Synthesis and turnover of folates in plants

被引:116
作者
Hanson, AD [1 ]
Gregory, JF
机构
[1] Univ Florida, Dept Hort Sci, Gainesville, FL 32611 USA
[2] Univ Florida, Dept Food Sci & Human Nutr, Gainesville, FL 32611 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
D O I
10.1016/S1369-5266(02)00249-2
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Folates are essential cofactors for one-carbon transfer reactions, which are central to plant metabolism. Plants synthesize folates de novo, and are key sources of dietary folate for humans. Research into plant folates therefore impacts human nutrition. Biochemical progress, the sequencing of the Arabidopsis genome, and EST databases are now painting a clear picture of the folate synthesis pathway in plants and its surprising compartmentation. Moreover, new analytical advances will help to elucidate plant folate turnover and transport, which are practically unexplored.
引用
收藏
页码:244 / 249
页数:6
相关论文
共 52 条
[1]  
Anguera MC, 2001, FASEB J, V15, pA955
[2]  
Bagley PJ, 1997, METHOD ENZYMOL, V281, P16
[3]  
Bagley PJ, 2000, CLIN CHEM, V46, P404
[4]  
BAILEY LB, 2001, PRESENT KNOWLEDGE NU, P214
[5]   Distribution of folate derivatives and enzymes for synthesis of 10-formyltetrahydrofolate in cytosolic and mitochondrial fractions of pea leaves [J].
Chen, LF ;
Chan, SY ;
Cossins, EA .
PLANT PHYSIOLOGY, 1997, 115 (01) :299-309
[6]  
Cossins E, 2000, CAN J BOT, V78, P691, DOI 10.1139/cjb-78-6-691
[7]   Folates and one-carbon metabolism in plants and fungi [J].
Cossins, EA ;
Chen, LF .
PHYTOCHEMISTRY, 1997, 45 (03) :437-452
[8]   Nutritional genomics: Manipulating plant micronutrients to improve human health [J].
DellaPenna, D .
SCIENCE, 1999, 285 (5426) :375-379
[9]   ENZYMATIC CHARACTERIZATION OF BACILLUS-SUBTILIS GTP CYCLOHYDROLASE-I - EVIDENCE FOR A CHEMICAL DEPHOSPHORYLATION OF DIHYDRONEOPTERIN TRIPHOSPHATE [J].
DESAIZIEU, A ;
VANKAN, P ;
VANLOON, APGM .
BIOCHEMICAL JOURNAL, 1995, 306 :371-377
[10]  
DEVRIES FWT, 1974, J THEOR BIOL, V45, P339, DOI DOI 10.1016/0022-5193(74)90119-2