An Insight to Chiral Monolith for Enantioselective Nano and Micro HPLC: Preparation and Applications

被引：25

作者：

Healey, Robert ^{[1
]}

Ghanem, Ashraf ^{[1
]}

机构：

[1] Univ Canberra, Fac Sci Appl, Chiral Program, Canberra, ACT 2617, Australia

来源：

CHIRALITY | 2013年 / 25卷 / 06期

关键词：

nano-HPLC; monolith; chiral selectors; chiral separation; silica monolith; HPLC; PERFORMANCE LIQUID-CHROMATOGRAPHY; SOL-GEL SYSTEM; CAPILLARY ELECTROCHROMATOGRAPHY; ENANTIOMERIC SEPARATION; STATIONARY PHASES; SILICA COLUMN; KINETIC PERFORMANCE; BETA-CYCLODEXTRIN; POLYMER MONOLITHS; POLYACRYLIC-ACID;

D O I：

10.1002/chir.22174

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

This review gives an overview of chiral separation principles and their application in enantioselective nano/micro high performance liquid chromatography (n/-HPLC) using chiral monolith. In particular, developments in silica and polymer chiral monolithic stationary phases are presented. The preparation and applications of chiral monoliths, the basic chiral separation principles and the mechanisms are discussed. Chirality 25:314-323, 2013. (c) 2013 Wiley Periodicals, Inc.

引用

页码：314 / 323

页数：10

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