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Microsatellites and their genomic distribution, evolution, function and applications: A review with special reference to fish genetics
被引:331
作者:
Chistiakov, Dimitry A.
Hellemans, Bart
Volckaert, Filip A. M.
机构:
[1] Univ Cincinnati, Med Ctr, Dept Pathol & Lab Med, Cincinnati, OH 45267 USA
[2] Katholieke Univ Leuven, Aquat Ecol Lab, B-3000 Louvain, Belgium
关键词:
evolution;
functional relevance;
genomic distribution;
microsatellite;
SSR;
Teleostei;
D O I:
10.1016/j.aquaculture.2005.11.031
中图分类号:
S9 [水产、渔业];
学科分类号:
0908 ;
摘要:
Microsatellites represent codominant molecular genetic markers, which are ubiquitously distributed within genomes. Due to their high level of polymorphism, relatively small size and rapid detection protocols, these markers are widely used in a variety of fundamental and applied fields of life and medical sciences. In the field of aquaculture, microsatellites represent workhorse markers, which are useful for the characterization of genetic stocks, broodstock selection, constructing dense linkage maps, mapping economically important quantitative traits, identifying genes responsible for these traits and application to marker-assisted breeding programmes. In this review, genomic distribution, function, evolution and practical applications of microsatellites are considered, with special emphasis on fish genetics and aquaculture. (c) 2005 Elsevier B.V. All rights reserved.
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页码:1 / 29
页数:29
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