Demographic and Clinical Differences Between Bipolar Disorder Patients With and Without Alcohol Use Disorders

被引：3

作者：

Xia, Yan ^{[1
]}

Ma, Dongying ^{[2
]}

Perich, Tania ^{[3
]}

Hu, Jian ^{[1
]}

Mitchell, Philip B. ^{[4
]}

机构：

[1] Harbin Med Univ, Affiliated Hosp 1, Mental Hlth Ctr, Mental Hlth Inst, Harbin, Peoples R China

[2] Harbin Med Univ, Affiliated Hosp 2, Dept Neurosurg, Harbin, Peoples R China

[3] Western Sydney Univ, Sch Psychol, Sydney, NSW, Australia

[4] Univ NSW, Sch Psychiat, Sydney, NSW, Australia

来源：

FRONTIERS IN PSYCHIATRY | 2020年 / 11卷

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

bipolar disorder; alcohol use disorder; comorbidity; sociodemographics; mental health; NATIONAL EPIDEMIOLOGIC SURVEY; SUBSTANCE USE DISORDERS; INTERNATIONAL DIAGNOSTIC INTERVIEW; COMORBID ANXIETY DISORDERS; COOCCURRING BIPOLAR; UNITED-STATES; LIFETIME PREVALENCE; SERVICE UTILIZATION; SPECTRUM DISORDER; MENTAL-DISORDERS;

D O I：

10.3389/fpsyt.2020.570574

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Background Bipolar disorder (BD) and alcohol use disorder (AUD) are two major independent causes of psychopathology in the general population. The prevalence of AUD in BD is high. Identifying the clinical and demographic features of patients with BD who may develop AUD could help with early identification and intervention. Methods Data from 238 patients diagnosed with BD were gathered on alcohol use, social demographics, longitudinal course of BD, clinical features of the most severe lifetime manic and depressive episodes, comorbid physical diseases, anxiety disorders, and other substance use disorders. Results We found that 74 of 238 BD patients had AUD (67 with alcohol dependence and 7 with alcohol abuse). Bivariate logistic regression analysis and multivariate logistic regression analysis found that the best predictors of AUD in patients with BD were being male (OR = 2.086, 95% CI = 1.094-3.979,p= 0.001), younger (OR = 0.965, 95% CI = 0.935-0.996,p= 0.026), and comorbidity with other unclassified substance dependence (OR = 10.817, 95% CI = 1.238-94.550,p= 0.031). Conclusions Male, younger current age, and having other substance use disorders were independently associated with AUD.

引用

页数：8