Reversal of mitochondrial abnormalities by CRISPR/Cas9 editing of the mutant HTT allele in vitro in Huntington's Disease patient-derived pluripotent and neural stem cells

被引:0
作者
Lopes, Carla [1 ,2 ]
Schlaeger, Thorsten [2 ,5 ]
de Almeida, Luis Pereira [1 ,6 ]
Daley, George [3 ,4 ,5 ,7 ]
Rego, Cristina [1 ,8 ]
机构
[1] Univ Coimbra, Ctr Neurosci & Cell Biol, Coimbra, Portugal
[2] Univ Coimbra, Inst Interdisciplinary Res, Coimbra, Portugal
[3] Boston Childrens Hosp, Div Hematol Oncol, Boston, MA USA
[4] Dana Farber Canc Inst, Boston, MA 02115 USA
[5] Boston Childrens Hosp, Stem Cell Program, Boston, MA USA
[6] Univ Coimbra, Fac Pharm, Coimbra, Portugal
[7] Harvard Med Sch, Harvard Stem Cell Inst, Boston, MA 02115 USA
[8] Univ Coimbra, Fac Med, Coimbra, Portugal
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D O I
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
S1-O10
引用
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页码:57 / 58
页数:2
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