Reversal of mitochondrial abnormalities by CRISPR/Cas9 editing of the mutant HTT allele in vitro in Huntington's Disease patient-derived pluripotent and neural stem cells

被引：0

作者：

Lopes, Carla ^{[1
,2
]}

Schlaeger, Thorsten ^{[2
,5
]}

de Almeida, Luis Pereira ^{[1
,6
]}

Daley, George ^{[3
,4
,5
,7
]}

Rego, Cristina ^{[1
,8
]}

机构：

[1] Univ Coimbra, Ctr Neurosci & Cell Biol, Coimbra, Portugal

[2] Univ Coimbra, Inst Interdisciplinary Res, Coimbra, Portugal

[3] Boston Childrens Hosp, Div Hematol Oncol, Boston, MA USA

[4] Dana Farber Canc Inst, Boston, MA 02115 USA

[5] Boston Childrens Hosp, Stem Cell Program, Boston, MA USA

[6] Univ Coimbra, Fac Pharm, Coimbra, Portugal

[7] Harvard Med Sch, Harvard Stem Cell Inst, Boston, MA 02115 USA

[8] Univ Coimbra, Fac Med, Coimbra, Portugal

来源：

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

S1-O10

引用

页码：57 / 58

页数：2