Draft genome of the river water buffalo

被引:32
作者
Mintoo, Abdul Awal [1 ,2 ,3 ]
Zhang, Hailin [4 ,5 ]
Chen, Chunhai [4 ]
Moniruzzaman, Mohammad [2 ,3 ]
Deng, Tingxian [6 ]
Anam, Mahbub [1 ,2 ,3 ]
Huque, Quazi Mohammad Emdadul [2 ,3 ]
Guang, Xuanmin [4 ]
Wang, Ping [4 ]
Zhong, Zhen [4 ]
Han, Pengfei [4 ]
Khatun, Asma [2 ]
Awal, Tabith M. [1 ,2 ,3 ]
Gao, Qiang [4 ]
Liang, Xianwei [6 ]
机构
[1] Lal Teer Seed Ltd, Dhaka, Bangladesh
[2] Lal Teer Livestock Ltd, Dhaka, Bangladesh
[3] MNT Life Sci Ctr, Gazipur, Bangladesh
[4] BGI Shenzhen, BGI Genom, Shenzhen, Peoples R China
[5] Univ Chinese Acad Sci, BGI Educ Ctr, Beijing, Peoples R China
[6] Chinese Acad Agr Sci, Buffalo Res Inst, Key Lab Buffalo Genet Breeding & Reprod Technol, Nanning, Peoples R China
关键词
annotation; genome; phylogenetic analysis; water buffalo; SEQUENCE; DATABASE; PREDICTION; ALIGNMENT; TOOL; PROGRAM; CATTLE; FINDER; BLAST;
D O I
10.1002/ece3.4965
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
Water buffalo (Bubalus bubalis), a large-sized member of the Bovidae family, is considered as an important livestock species throughout Southeast Asia. In order to better understand the molecular basis of buffalo improvement and breeding, we sequenced and assembled the genome (2n=50) of a river buffalo species Bubalus bubalis from Bangladesh. Its genome size is 2.77 Gb, with a contig N50 of 25 kb and the scaffold N50 of 6.9 Mbp. Based on the assembled genome, we annotated 24,613 genes for future functional genomics studies. Phylogenetic tree analysis of cattle and water buffalo lineages showed that they diverged about 5.8-9.8 million years ago. Our findings provide an insight into the water buffalo genome which will contribute in further research on buffalo such as molecular breeding, understanding complex traits, conservation, and biodiversity.
引用
收藏
页码:3378 / 3388
页数:11
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