Five questions to consider before conducting a stepped wedge trial

被引：47

作者：

Hargreaves, James R. ^{[1
]}

Copas, Andrew J. ^{[2
]}

Beard, Emma ^{[3
,4
]}

Osrin, David ^{[5
]}

Lewis, James J. ^{[6
]}

Davey, Calum ^{[1
]}

Thompson, Jennifer A. ^{[6
]}

Baio, Gianluca ^{[7
]}

Fielding, Katherine L. ^{[6
]}

Prost, Audrey ^{[5
]}

机构：

[1] London Sch Hyg & Trop Med, Dept Social & Environm Hlth Res, London WC1, England

[2] UCL, MRC Clin Trials Unit, London, England

[3] UCL, Dept Clin Educ & Hlth Psychol, London, England

[4] UCL, Dept Epidemiol & Publ Hlth, London, England

[5] UCL, Inst Global Hlth, London, England

[6] London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, London WC1, England

[7] UCL, Dept Stat Sci, London, England

来源：

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

Methodology; Public health; Stepped wedge trials; CLUSTER-RANDOMIZED-TRIAL; DESIGN; EQUIPOISE; ETHICS;

D O I：

10.1186/s13063-015-0841-8

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Researchers should consider five questions before starting a stepped wedge trial.

引用

页数：4

共 29 条

[1] [Anonymous], 1987, CANCER RES, V47, P5782
[2] Sample size calculation for a stepped wedge trial
Baio, Gianluca
Copas, Andrew
Ambler, Gareth
Hargreaves, James
Beard, Emma
Omar, Rumana Z.
[J]. TRIALS, 2015, 16
[3] The effect of training doctors in communication skills on women's satisfaction with doctor-woman relationship during labour and delivery: a stepped wedge cluster randomised trial in Damascus
Bashour, Hyam N.
Kanaan, Mona
Kharouf, Mayada H.
Abdulsalam, Asmaa A.
Tabbaa, Mohammed A.
Cheikha, Salah A.
[J]. BMJ OPEN, 2013, 3 (08):
[4] Beard E, 2015, TRIALS
[5] Brown CA., 2006, BMC MED RES METHODOL, V6, P54, DOI DOI 10.1186/1471-2288-6-54
[6] Butler D, 2014, NATURE NEWS BLOG
[7] Copas AJ., 2015, TRIALS
[8] Davey C., 2015, TRIALS
[9] Davey C, 2015, INT J EPIDE IN PRESS
[10] EQUIPOISE AND THE ETHICS OF CLINICAL RESEARCH
FREEDMAN, B
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (03) : 141 - 145