Molecular identification and risk factor analysis of the first Lumpy skin disease outbreak in cattle in Mongolia

被引:10
作者
Odonchimeg, Myagmarsuren [1 ]
Erdenechimeg, Dashzevge [1 ]
Tuvshinbayar, Adiyasuren [2 ]
Tsogtgerel, Munkhtuul [3 ]
Bazarragchaa, Enkhbold [4 ]
Ulaankhuu, Ankhanbaatar [4 ]
Selenge, Tsend [5 ]
Munkhgerel, Dalantai [1 ]
Munkhtsetseg, Ariunbold [1 ]
Altanchimeg, Adilbish [1 ]
Odbileg, Raadan [1 ]
Soyolmaa, Gurdorj [1 ]
Enkhmandakh, Yondonjamts [1 ]
Batmagnai, Enkhbaatar [1 ]
Sugar, Sengee [6 ]
Kimura, Takashi [7 ]
Sugimoto, Chihiro [8 ]
Isoda, Norikazu [9 ]
Batsukh, Basan [2 ]
Sakoda, Yoshihiro [9 ]
机构
[1] Mongolian Univ Life Sci, Inst Vet Med, Ulaanbaatar, Mongolia
[2] Minist Food Agr & Light Ind, Gen Author Vet Serv, Ulaanbaatar, Mongolia
[3] Mongolian Univ Life Sci, Sch Vet Med, Ulaanbaatar, Mongolia
[4] State Cent Vet Lab, Div Transboundary & Infect Dis Diag & Surveillanc, Ulaanbaatar, Mongolia
[5] Livestock Commercializat Project, Ulaanbaatar, Mongolia
[6] Malchin Mongol LLC, Ulaanbaatar, Mongolia
[7] Hokkaido Univ, Fac Vet Med, Dept Clin Sci, Lab Comparat Pathol, Sapporo, Hokkaido, Japan
[8] Japan Int Cooperat Agcy, Project Strengthening Pract Capac Publ & Private, Ulaanbaatar, Mongolia
[9] Hokkaido Univ, Fac Vet Med, Dept Dis Control, Lab Microbiol, Sapporo, Hokkaido 0600818, Japan
关键词
lumpy skin disease; molecular identification; Mongolia; outbreak; risk factor; MECHANICAL TRANSMISSION; VIRUS; SAMPLES; THREAT; GENOME;
D O I
10.1292/jvms.22-0250
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Lumpy skin disease (LSD) is a transboundary viral infectious disease in cattle caused by a Capripoxvirus. LSD has been recently introduced in some Asian countries. However, in Mongolia, no report of LSD is publicly available. We clinically examined LSD symptoms in 1,034 cattle from 4 soum (district) in Dornod province in Mongolia. Sixty-one cattle of them were confirmed with symptoms of LSD and then viral P32 gene was detected by a PCR. The overall prevalence of LSD in cattle was 5.9%. Females odds ratios (OR)=2.27 than males, adults (>2.5-years-old, OR=3.68) than young (1-2.5-years-old) and calves (<1-year-old) were at higher risks for LSD cases in Mongolia, while locations near the tube well and pond water are major risk areas for viral transmission due to density of insects often is high. For virus isolation, skin nodule tissue samples of 4 cattle located in four distinct soums were used for viral propagation using the MDBK cell line. Internal terminal repeat region and RPO30 gene of 4 Mongolian isolates were amplified and sequenced. In the phylogenetic trees, Mongolian LSDVs (2021) were clustered together with the Chinese (2020) and Vietnamese isolates (2020). This is the first report alarming the LSD outbreak in Mongolia that was confirmed by our study. The newly isolated viruses would be a useful base for developing diagnostic tools and inactivated vaccine technology. A large-scale study of LSD is next priority for establishing successful control strategy of further disease outbreak.
引用
收藏
页码:1244 / 1252
页数:9
相关论文
共 34 条
[1]   Sporadic cases of lumpy skin disease among cattle in Sharkia province, Egypt: Genetic characterization of lumpy skin disease virus isolates and pathological findings [J].
Abdallah, Fatma M. ;
El Damaty, Hend M. ;
Kotb, Gamilat F. .
VETERINARY WORLD, 2018, 11 (08) :1150-1158
[2]   Sero-prevalence of lumpy skin disease in selected districts of West Wollega zone, Ethiopia [J].
Abera, Zelalem A ;
Degefu, Hailu ;
Gari, Getachew ;
Kidane, Menbere .
BMC VETERINARY RESEARCH, 2015, 11
[3]  
Al-Salihi K.A., 2014, MRSVA, V3, P6, DOI DOI 10.22428/MRVSA.2307-8073.2014.00332.X
[4]   The First Lumpy Skin Disease Outbreak in Thailand (2021): Epidemiological Features and Spatio-Temporal Analysis [J].
Arjkumpa, Orapun ;
Suwannaboon, Minta ;
Boonrod, Manoch ;
Punyawan, Issara ;
Liangchaisiri, Supawadee ;
Laobannue, Patchariya ;
Lapchareonwong, Chayanun ;
Sansri, Chaiwat ;
Kuatako, Noppasorn ;
Panyasomboonying, Pawares ;
Uttarak, Ponkrit ;
Buamithup, Noppawan ;
Sansamur, Chalutwan ;
Punyapornwithaya, Veerasak .
FRONTIERS IN VETERINARY SCIENCE, 2022, 8
[5]   EDITORIAL Lumpy skin disease: a direct threat to Europe [J].
Beard, Philippa M. .
VETERINARY RECORD, 2016, 178 (22) :557-558
[6]   AN INVESTIGATION OF POSSIBLE ROUTES OF TRANSMISSION OF LUMPY SKIN-DISEASE VIRUS (NEETHLING) [J].
CARN, VM ;
KITCHING, RP .
EPIDEMIOLOGY AND INFECTION, 1995, 114 (01) :219-226
[7]   Attempted mechanical transmission of lumpy skin disease virus by biting insects [J].
Chihota, CM ;
Rennie, LF ;
Kitching, RP ;
Mellor, PS .
MEDICAL AND VETERINARY ENTOMOLOGY, 2003, 17 (03) :294-300
[8]   Mechanical transmission of lumpy skin disease virus by Aedes aegypti (Diptera: Culicidae) [J].
Chihota, CM ;
Rennie, LF ;
Kitching, RP ;
Mellor, PS .
EPIDEMIOLOGY AND INFECTION, 2001, 126 (02) :317-321
[9]  
DAVIES FG, 1991, BRIT VET J, V147, P489, DOI 10.1016/0007-1935(91)90019-J
[10]  
El-Neweshy MS, 2013, PAK VET J, V33, P60