Short-Term Complications of Membranous Nephropathy

被引:15
作者
Barbour, Sean [1 ]
Reich, Heather [2 ]
Cattran, Daniel [2 ]
机构
[1] Univ British Columbia, Dept Med, Div Nephrol, Vancouver, BC, Canada
[2] Univ Toronto, Dept Med, Div Nephrol, Toronto, ON, Canada
来源
NEW INSIGHTS INTO GLOMERULONEPHRITIS: PATHOGENESIS AND TREATMENT | 2013年 / 181卷
关键词
RENAL-VEIN THROMBOSIS; NEPHROTIC SYNDROME; PROPHYLACTIC ANTICOAGULATION; THROMBOEMBOLIC COMPLICATIONS; VENOUS THROMBOEMBOLISM; RISK-FACTORS; PROTEINURIA; ACTIVATION; DISEASE; EVENTS;
D O I
10.1159/000349976
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Short-term complications of membranous nephropathy (MN) are important components of the process and their proper management can significantly alter the outcomes of patients with this disease. These complications vary from the non-specific ones associated with many types of chronic kidney disease such as hypertension, proteinuria and the symptoms associated with the nephrotic syndrome including edema and dyslipidemia. These are briefly discussed in the chapter. In addition, there are some specific issues more commonly associated with MN than other types of glomerulonephritis. This includes a hypercoagulable state and the associated thromboembolism. There is more recent information in this domain and this is included in the chapter. The associated increased risk of infection in MN patients is the final chapter component. This section is included to remind us not only of the direct impact of that disease process on reducing resistance to infection, but also to indicate the need to consider prophylactic antibiotics when the addition of potent immunosuppressive drug treatment is required for these patients. Copyright (C) 2013 S. Karger AG, Basel
引用
收藏
页码:143 / 151
页数:9
相关论文
共 30 条
[1]  
[Anonymous], KIDNEY INT S
[2]   Disease-specific risk of venous thromboembolic events is increased in idiopathic glomerulonephritis [J].
Barbour, Sean J. ;
Greenwald, Allen ;
Djurdjev, Ognjenka ;
Levin, Adeera ;
Hladunewich, Michelle A. ;
Nachman, Patrick H. ;
Hogan, Susan L. ;
Cattran, Daniel C. ;
Reich, Heather N. .
KIDNEY INTERNATIONAL, 2012, 81 (02) :190-195
[3]   Characterization of proteinuria in primary glomerulonephritides: Urinary polymers of albumin [J].
Bazzi, C ;
Petrini, C ;
Rizza, V ;
Arrigo, G ;
Beltrame, A ;
DAmico, G .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1997, 30 (03) :404-412
[4]   MEMBRANOUS NEPHROPATHY AND THROMBOEMBOLISM - IS PROPHYLACTIC ANTICOAGULATION WARRANTED [J].
BELLOMO, R ;
ATKINS, RC .
NEPHRON, 1993, 63 (03) :249-254
[5]   RENAL-VEIN THROMBOSIS IN NEPHROTIC SYNDROME - A PROSPECTIVE-STUDY AND REVIEW [J].
CHUGH, KS ;
GUPTA, VK ;
SURI, S ;
MALIK, N ;
AGGARWAL, ML ;
UBEROI, HS ;
SINGHAL, PC ;
JAIN, SK .
POSTGRADUATE MEDICAL JOURNAL, 1981, 57 (671) :566-570
[6]   Hemostatic problems and thromboembolic complications in nephrotic children [J].
Citak, A ;
Emre, S ;
Sirin, A ;
Bilge, I ;
Nayir, A .
PEDIATRIC NEPHROLOGY, 2000, 14 (02) :138-142
[7]  
Craig JC, 2008, EVIDENCE BASED NEPHR, P311
[8]   A New Risk Scheme to Predict Warfarin-Associated Hemorrhage The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study [J].
Fang, Margaret C. ;
Go, Alan S. ;
Chang, Yuchiao ;
Borowsky, Leila H. ;
Pomernacki, Niela K. ;
Udaltsova, Natalia ;
Singer, Daniel E. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 58 (04) :395-401
[9]   Varicella vaccination in children with nephrotic syndrome: A report of the Southwest Pediatric Nephrology Study Group [J].
Furth, SL ;
Arbus, GS ;
Hogg, R ;
Tarver, J ;
Chan, C ;
Fivush, BA .
JOURNAL OF PEDIATRICS, 2003, 142 (02) :145-148
[10]   Prophylactic anticoagulation in nephrotic syndrome: A clinical conundrum [J].
Glassock, Richard J. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2007, 18 (08) :2221-2225