Growth Retardation in Children with Kidney Disease

被引:25
作者
Salas, Paulina [1 ]
Pinto, Viola [1 ]
Rodriguez, Josefina [2 ]
Jose Zambrano, Maria [3 ]
Mericq, Veronica [4 ]
机构
[1] Hosp Exequiel Gonzalez Cortes, Pediat Nephrol Unit, Santiago, Chile
[2] Univ Chile, Fac Med, Santiago 7, Chile
[3] Catholic Univ Chile, Fac Med, Santiago, Chile
[4] Univ Chile, Fac Med, Inst Maternal & Child Res, Santiago 7, Chile
关键词
CHRONIC-RENAL-FAILURE; FACTOR-I; HORMONE TREATMENT; STEROID WITHDRAWAL; TRANSPLANT; SECRETION; UREMIA; AXIS; HEMODIALYSIS; RESISTANCE;
D O I
10.1155/2013/970946
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Growth failure is almost inextricably linked with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Growth failure in CKD has been associated with both increased morbidity and mortality. Growth failure in the setting of kidney disease is multifactorial and is related to poor nutritional status as well as comorbidities, such as anemia, bone and mineral disorders, and alterations in hormonal responses, as well as to aspects of treatment such as steroid exposure. This review covers updated management of growth failure in these children including adequate nutrition, treatment of metabolic alterations, and early administration of recombinant human growth hormone (GH).
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页数:8
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