Preparation of stereocomplex and pseudo-polyrotaxane with various cyclodextrins as wheel components using triblock copolymer of poly(ethylene glycol) and polylactide

The ABA-type triblock-copolymers (BCPs) of polylactide (PLA) and poly(ethylene glycol) (PEG) were synthesized as axle components for rotaxane formation. It is known that alpha-cyclodextrin (CD) exists near the PEG moiety in pseudo-polyrotaxane (PPRX), and the PLA moiety can form a stereocomplex (SC), by mixing with l- and d-isomers. In this study, various CDs, including beta-CD and gamma-CD, were used as wheel components, and effects of CD structures on both PPRX and SC formations were studied. The solubility of CDs is influenced to form the PPRX, resulting in differing numbers of CDs in the axle. PPRX structures were investigated by H-1 NMR, NOESY, and DOSY, and SC structures were investigated by FT-IR and XRD. Their thermal properties were also evaluated by DSC and TGA, to consider the physical properties of the simultaneous formation of PPRX and SC. This study gave insight into the complicated host-guest and polymer-polymer interactions.