Synthesis, X-ray structure, and hydrolytic chemistry of the highly potent antiviral polyniobotungstate A-α-[Si2Nb6W18O77]8-

被引：34

作者：

Kim, GS

Zeng, HD

Rhule, JT

Weinstock, IA

Hill, CL

机构：

[1] Emory Univ, Dept Chem, Atlanta, GA 30322 USA

[2] Kangweon Natl Univ, Dept Sci Educ, Chunchon 200701, South Korea

[3] US Forest Serv, Forest Prod Lab, Madison, WI 53705 USA

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 17期

关键词：

D O I：

10.1039/a903983j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Potently antiviral polyniobotungstates have been structurally characterized; the dimer A-alpha-[Si2Nb6W18O77](8-) cleaves cleanly to the monomer A-alpha-[SiNb3W9O40](7-) within 1 min in aqueous solution buffered at physiological (neutral) pH establishing that the monomer and not the dimer is pharmacologically relevant.

引用

页码：1651 / 1652

页数：2

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