Reduction of severe acute graft-versus-host disease using a combination of pre transplant anti-thymocyte globulin and post-transplant cyclophosphamide in matched unrelated donor transplantation

被引:27
作者
Deotare, Uday [1 ]
Atenafu, Eshetu G. [2 ]
Loach, David [1 ]
Michelis, Fotios V. [1 ]
Kim, Dennis [1 ]
Thyagu, Santhosh [1 ]
Lipton, Jeffrey H. [1 ]
Messner, Hans A. [1 ]
Viswabandya, Auro [1 ]
机构
[1] Univ Hlth Network, Princess Margaret Canc Ctr, Dept Med Oncol & Hematol, Allogene Blood & Marrow Transplant Program, Toronto, ON, Canada
[2] Univ Hlth Network, Dept Biostat, Princess Margaret Canc Ctr, Toronto, ON, Canada
关键词
HEMATOPOIETIC-CELL TRANSPLANTATION; HIGH-DOSE CYCLOPHOSPHAMIDE; MARROW-TRANSPLANTATION; SINGLE-AGENT; OPEN-LABEL; MALIGNANCIES; PROPHYLAXIS; BLOOD; MORTALITY; PHASE-3;
D O I
10.1038/s41409-017-0053-9
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:361 / 365
页数:5
相关论文
共 12 条
[1]   Thymoglobulin prevents chronic graft-versus-host disease, chronic lung dysfunction, and late transplant-related mortality: Long-term follow-up of a randomized trial in patients undergoing unrelated donor transplantation [J].
Bacigalupo, A ;
Lamparelli, T ;
Barisione, G ;
Bruzzi, P ;
Guidi, S ;
Alessandrino, PE ;
di Bartolomeo, P ;
Oneto, R ;
Bruno, B ;
Sacchi, N ;
van Lint, MT ;
Bosi, A .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2006, 12 (05) :560-565
[2]   T-Cell-Replete HLA-Haploidentical Hematopoietic Transplantation for Hematologic Malignancies Using Post-Transplantation Cyclophosphamide Results in Outcomes Equivalent to Those of Contemporaneous HLA-Matched Related and Unrelated Donor Transplantation [J].
Bashey, Asad ;
Zhang, Xu ;
Sizemore, Connie A. ;
Manion, Karen ;
Brown, Stacey ;
Holland, H. Kent ;
Morris, Lawrence E. ;
Solomon, Scott R. .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (10) :1310-1316
[3]   Single-Agent High-Dose Cyclophosphamide for Graft-versus-Host Disease Prophylaxis in Human Leukocyte Antigen-Matched Reduced-Intensity Peripheral Blood Stem Cell Transplantation Results in an Unacceptably High Rate of Severe Acute Graft-versus-Host Disease [J].
Bradstock, Kenneth F. ;
Bilmon, Ian ;
Kwan, John ;
Micklethwaite, Kenneth ;
Blyth, Emily ;
Deren, Stephanie ;
Bayley, Angela ;
Gebski, Val ;
Gottlieb, David .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2015, 21 (05) :941-944
[4]   Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial [J].
Finke, Juergen ;
Bethge, Wolfgang A. ;
Schmoor, Claudia ;
Ottinger, Hellmut D. ;
Stelljes, Matthias ;
Zander, Axel R. ;
Volin, Liisa ;
Ruutu, Tapani ;
Heim, Dominik A. ;
Schwerdtfeger, Rainer ;
Kolbe, Karin ;
Mayer, Jiri ;
Maertens, Johan A. ;
Linkesch, Werner ;
Holler, Ernst ;
Koza, Vladimir ;
Bornhaeuser, Martin ;
Einsele, Hermann ;
Kolb, Hans-Jochem ;
Bertz, Hartmut ;
Egger, Matthias ;
Grishina, Olga ;
Socie, Gerard .
LANCET ONCOLOGY, 2009, 10 (09) :855-864
[5]   Absence of Post-Transplantation Lymphoproliferative Disorder after Allogeneic Blood or Marrow Transplantation Using Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis [J].
Kanakry, Jennifer A. ;
Kasamon, Yvette L. ;
Bolanos-Meade, Javier ;
Borrello, Ivan M. ;
Brodsky, Robert A. ;
Fuchs, Ephraim J. ;
Ghosh, Nilanjan ;
Gladstone, Douglas E. ;
Gocke, Christopher D. ;
Huff, Carol Ann ;
Kanakry, Christopher G. ;
Luznik, Leo ;
Matsui, William ;
Mogri, Huzefa J. ;
Swinnen, Lode J. ;
Symons, Heather J. ;
Jones, Richard J. ;
Anibinder, Richard E. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (10) :1514-1517
[6]   HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide [J].
Luznik, Leo ;
O'Donnell, Paul V. ;
Symons, Heather J. ;
Chen, Allen R. ;
Leffell, M. Susan ;
Zahurak, Marianna ;
Gooley, Ted A. ;
Piantadosi, Steve ;
Kaup, Michele ;
Ambinder, Richard F. ;
Huff, Carol Ann ;
Matsui, William ;
Bolanos-Meade, Javier ;
Borrello, Ivan ;
Powell, Jonathan D. ;
Harrington, Elizabeth ;
Warnock, Sandy ;
Flowers, May ;
Brodsky, Robert A. ;
Sandmaier, Brenda M. ;
Storb, Rainer F. ;
Jones, Richard J. ;
Fuchs, Ephraim J. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2008, 14 (06) :641-650
[7]   Post-Transplantation Cyclophosphamide for Tolerance Induction in HLA-Haploidentical Bone Marrow Transplantation [J].
Luznik, Leo ;
O'Donnell, Paul V. ;
Fuchs, Ephraim J. .
SEMINARS IN ONCOLOGY, 2012, 39 (06) :683-693
[8]   High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease [J].
Luznik, Leo ;
Bolanos-Meade, Javier ;
Zahurak, Marianna ;
Chen, Allen R. ;
Smith, B. Douglas ;
Brodsky, Robert ;
Huff, Carol Ann ;
Borrello, Ivan ;
Matsui, William ;
Powell, Jonathan D. ;
Kasamon, Yvette ;
Goodman, Steven N. ;
Hess, Allan ;
Levitsky, Hyam I. ;
Ambinder, Richard F. ;
Jones, Richard J. ;
Fuchs, Ephraim J. .
BLOOD, 2010, 115 (16) :3224-3230
[9]   The Addition of 400 cGY Total Body Irradiation to a Regimen Incorporating Once-Daily Intravenous Busulfan, Fludarabine, and Antithymocyte Globulin Reduces Relapse Without Affecting Nonrelapse Mortality in Acute Myelogenous Leukemia [J].
Russell, James A. ;
Irish, William ;
Balogh, Alexander ;
Chaudhry, M. Ahsan ;
Savoie, Mary Lynn ;
Turner, A. Robert ;
Larratt, Loree ;
Storek, Jan ;
Bahlis, Nizar J. ;
Brown, Christopher B. ;
Quinlan, Diana ;
Geddes, Michelle ;
Zacarias, Nancy ;
Daly, Andrew ;
Duggan, Peter ;
Stewart, Douglas A. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (04) :509-514
[10]   Myeloablative versus Reduced-Intensity Conditioning in Patients with Myeloid Malignancies: A Propensity Score-Matched Analysis [J].
Sibai, Hassan ;
Falcone, Umberto ;
Deotare, Uday ;
Michelis, Fotios V. ;
Uhm, Jieun ;
Gupta, Vikas ;
Kuruvilla, John ;
Lipton, Jeffrey H. ;
Seftel, Matthew D. ;
Messner, Hans A. ;
Kim, Dennis .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2016, 22 (12) :2270-2275