Reduction of severe acute graft-versus-host disease using a combination of pre transplant anti-thymocyte globulin and post-transplant cyclophosphamide in matched unrelated donor transplantation

被引:26
作者
Deotare, Uday [1 ]
Atenafu, Eshetu G. [2 ]
Loach, David [1 ]
Michelis, Fotios V. [1 ]
Kim, Dennis [1 ]
Thyagu, Santhosh [1 ]
Lipton, Jeffrey H. [1 ]
Messner, Hans A. [1 ]
Viswabandya, Auro [1 ]
机构
[1] Univ Hlth Network, Princess Margaret Canc Ctr, Dept Med Oncol & Hematol, Allogene Blood & Marrow Transplant Program, Toronto, ON, Canada
[2] Univ Hlth Network, Dept Biostat, Princess Margaret Canc Ctr, Toronto, ON, Canada
关键词
HEMATOPOIETIC-CELL TRANSPLANTATION; HIGH-DOSE CYCLOPHOSPHAMIDE; MARROW-TRANSPLANTATION; SINGLE-AGENT; OPEN-LABEL; MALIGNANCIES; PROPHYLAXIS; BLOOD; MORTALITY; PHASE-3;
D O I
10.1038/s41409-017-0053-9
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:361 / 365
页数:5
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共 12 条
  • [1] Thymoglobulin prevents chronic graft-versus-host disease, chronic lung dysfunction, and late transplant-related mortality: Long-term follow-up of a randomized trial in patients undergoing unrelated donor transplantation
    Bacigalupo, A
    Lamparelli, T
    Barisione, G
    Bruzzi, P
    Guidi, S
    Alessandrino, PE
    di Bartolomeo, P
    Oneto, R
    Bruno, B
    Sacchi, N
    van Lint, MT
    Bosi, A
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2006, 12 (05) : 560 - 565
  • [2] T-Cell-Replete HLA-Haploidentical Hematopoietic Transplantation for Hematologic Malignancies Using Post-Transplantation Cyclophosphamide Results in Outcomes Equivalent to Those of Contemporaneous HLA-Matched Related and Unrelated Donor Transplantation
    Bashey, Asad
    Zhang, Xu
    Sizemore, Connie A.
    Manion, Karen
    Brown, Stacey
    Holland, H. Kent
    Morris, Lawrence E.
    Solomon, Scott R.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (10) : 1310 - 1316
  • [3] Single-Agent High-Dose Cyclophosphamide for Graft-versus-Host Disease Prophylaxis in Human Leukocyte Antigen-Matched Reduced-Intensity Peripheral Blood Stem Cell Transplantation Results in an Unacceptably High Rate of Severe Acute Graft-versus-Host Disease
    Bradstock, Kenneth F.
    Bilmon, Ian
    Kwan, John
    Micklethwaite, Kenneth
    Blyth, Emily
    Deren, Stephanie
    Bayley, Angela
    Gebski, Val
    Gottlieb, David
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2015, 21 (05) : 941 - 944
  • [4] Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial
    Finke, Juergen
    Bethge, Wolfgang A.
    Schmoor, Claudia
    Ottinger, Hellmut D.
    Stelljes, Matthias
    Zander, Axel R.
    Volin, Liisa
    Ruutu, Tapani
    Heim, Dominik A.
    Schwerdtfeger, Rainer
    Kolbe, Karin
    Mayer, Jiri
    Maertens, Johan A.
    Linkesch, Werner
    Holler, Ernst
    Koza, Vladimir
    Bornhaeuser, Martin
    Einsele, Hermann
    Kolb, Hans-Jochem
    Bertz, Hartmut
    Egger, Matthias
    Grishina, Olga
    Socie, Gerard
    [J]. LANCET ONCOLOGY, 2009, 10 (09) : 855 - 864
  • [5] Absence of Post-Transplantation Lymphoproliferative Disorder after Allogeneic Blood or Marrow Transplantation Using Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis
    Kanakry, Jennifer A.
    Kasamon, Yvette L.
    Bolanos-Meade, Javier
    Borrello, Ivan M.
    Brodsky, Robert A.
    Fuchs, Ephraim J.
    Ghosh, Nilanjan
    Gladstone, Douglas E.
    Gocke, Christopher D.
    Huff, Carol Ann
    Kanakry, Christopher G.
    Luznik, Leo
    Matsui, William
    Mogri, Huzefa J.
    Swinnen, Lode J.
    Symons, Heather J.
    Jones, Richard J.
    Anibinder, Richard E.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (10) : 1514 - 1517
  • [6] HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide
    Luznik, Leo
    O'Donnell, Paul V.
    Symons, Heather J.
    Chen, Allen R.
    Leffell, M. Susan
    Zahurak, Marianna
    Gooley, Ted A.
    Piantadosi, Steve
    Kaup, Michele
    Ambinder, Richard F.
    Huff, Carol Ann
    Matsui, William
    Bolanos-Meade, Javier
    Borrello, Ivan
    Powell, Jonathan D.
    Harrington, Elizabeth
    Warnock, Sandy
    Flowers, May
    Brodsky, Robert A.
    Sandmaier, Brenda M.
    Storb, Rainer F.
    Jones, Richard J.
    Fuchs, Ephraim J.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2008, 14 (06) : 641 - 650
  • [7] Post-Transplantation Cyclophosphamide for Tolerance Induction in HLA-Haploidentical Bone Marrow Transplantation
    Luznik, Leo
    O'Donnell, Paul V.
    Fuchs, Ephraim J.
    [J]. SEMINARS IN ONCOLOGY, 2012, 39 (06) : 683 - 693
  • [8] High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease
    Luznik, Leo
    Bolanos-Meade, Javier
    Zahurak, Marianna
    Chen, Allen R.
    Smith, B. Douglas
    Brodsky, Robert
    Huff, Carol Ann
    Borrello, Ivan
    Matsui, William
    Powell, Jonathan D.
    Kasamon, Yvette
    Goodman, Steven N.
    Hess, Allan
    Levitsky, Hyam I.
    Ambinder, Richard F.
    Jones, Richard J.
    Fuchs, Ephraim J.
    [J]. BLOOD, 2010, 115 (16) : 3224 - 3230
  • [9] The Addition of 400 cGY Total Body Irradiation to a Regimen Incorporating Once-Daily Intravenous Busulfan, Fludarabine, and Antithymocyte Globulin Reduces Relapse Without Affecting Nonrelapse Mortality in Acute Myelogenous Leukemia
    Russell, James A.
    Irish, William
    Balogh, Alexander
    Chaudhry, M. Ahsan
    Savoie, Mary Lynn
    Turner, A. Robert
    Larratt, Loree
    Storek, Jan
    Bahlis, Nizar J.
    Brown, Christopher B.
    Quinlan, Diana
    Geddes, Michelle
    Zacarias, Nancy
    Daly, Andrew
    Duggan, Peter
    Stewart, Douglas A.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (04) : 509 - 514
  • [10] Myeloablative versus Reduced-Intensity Conditioning in Patients with Myeloid Malignancies: A Propensity Score-Matched Analysis
    Sibai, Hassan
    Falcone, Umberto
    Deotare, Uday
    Michelis, Fotios V.
    Uhm, Jieun
    Gupta, Vikas
    Kuruvilla, John
    Lipton, Jeffrey H.
    Seftel, Matthew D.
    Messner, Hans A.
    Kim, Dennis
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2016, 22 (12) : 2270 - 2275