Statins: the next step in adjuvant therapy for sepsis?

[1] Prior statin therapy is associated with a decreased rate of severe sepsis [J]. CIRCULATION, 2004, 110 (07) : 880 - 885

[2] Ando H, 2000, J PHARMACOL EXP THER, V294, P1043

[3] Arnaud C, 2005, ARCH MAL COEUR VAISS, V98, P661

[4] Intensive versus moderate lipid lowering with statins after acute coronary syndromes [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (15) : 1495 - 1504

[5] HMG-CoA reductase inhibitors for lowering elevated levels of C-reactive protein [J]. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2004, 61 (16) : 1676 - 1681

[6] Collins R, 2002, LANCET, V360, P7, DOI 10.1016/S0140-6736(02)09327-3

[7] In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (08) : 1327 - 1332

[8] Statin therapy prior to ICU admission: protection against infection or a severity marker? [J]. INTENSIVE CARE MEDICINE, 2006, 32 (01) : 160 - 164

[9] Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats [J]. SHOCK, 2004, 21 (03): : 271 - 275

[10] Simvastatin reduces NF-κB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet [J]. CARDIOVASCULAR RESEARCH, 2003, 57 (01) : 168 - 177

[1] Prior statin therapy is associated with a decreased rate of severe sepsis [J]. CIRCULATION, 2004, 110 (07) : 880 - 885

[2] Ando H, 2000, J PHARMACOL EXP THER, V294, P1043

[3] Arnaud C, 2005, ARCH MAL COEUR VAISS, V98, P661

[4] Intensive versus moderate lipid lowering with statins after acute coronary syndromes [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (15) : 1495 - 1504

[5] HMG-CoA reductase inhibitors for lowering elevated levels of C-reactive protein [J]. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2004, 61 (16) : 1676 - 1681

[6] Collins R, 2002, LANCET, V360, P7, DOI 10.1016/S0140-6736(02)09327-3

[7] In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (08) : 1327 - 1332

[8] Statin therapy prior to ICU admission: protection against infection or a severity marker? [J]. INTENSIVE CARE MEDICINE, 2006, 32 (01) : 160 - 164

[9] Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats [J]. SHOCK, 2004, 21 (03): : 271 - 275

[10] Simvastatin reduces NF-κB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet [J]. CARDIOVASCULAR RESEARCH, 2003, 57 (01) : 168 - 177