The Histone Deacetylase Inhibitor FK228 Increases Histone Acetylation, Coxsackie Adenovirus Receptor Levels and Adenovirus Transgene Expression in Human LOX IMVI Melanoma Xenografts

被引：0
|
作者：
Goldsmith, Merrill E. [1 ]
Steadman, Kenneth [1 ]
Aguila, Alian [1 ]
Alley, Michael C. [2 ]
Waud, William R. [3 ]
Bates, Susan [1 ]
Fojo, Tito [1 ]
机构：
[1] NCI, Med Oncol Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
[2] NCI, Biol Testing Branch, Div Canc Treatment & Diag, NIH, Frederick, MD 21701 USA
[3] So Res Inst, Birmingham, AL 35255 USA
来源：
MOLECULAR THERAPY | 2006年 / 13卷
关键词：
D O I：
10.1016/j.ymthe.2006.08.349
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
294
引用
收藏
页码：S112 / S112
页数：1
相关论文
共 41 条
  • [1] Coxsackie-adenovirus receptor (CAR) levels can be increased in human xenografts followed by treatment with FK228, a histone deacetylase inhibitor
    Aguila, A
    Goldsmith, ME
    Gollapalli, SJ
    Alley, MC
    Waud, WW
    Bates, S
    Fojo, T
    MOLECULAR THERAPY, 2004, 9 : S234 - S234
  • [2] The histone deacetylase inhibitor FK228 preferentially enhances adenovirus transgene expression in malignant cells
    Goldsmith, ME
    Kitazono, M
    Fok, P
    Aikou, T
    Bates, S
    Fojo, T
    CLINICAL CANCER RESEARCH, 2003, 9 (14) : 5394 - 5401
  • [3] Coxsackie-adenovirus receptor (CAR) levels are increased in two human melanoma xenograft mouse model systems by treatment with the histone deacetylase inhibitor FK228
    Goldsmith, ME
    Alley, MC
    Waud, WR
    Fok, P
    Bates, S
    Fojo, T
    MOLECULAR THERAPY, 2003, 7 (05) : S427 - S428
  • [4] The histone deacetylase inhibitor FK228 given prior to adenovirus infection can boost infection in melanoma xenograft model systems
    Goldsmith, Merrill E.
    Aguila, Alian
    Steadman, Kenneth
    Martinez, Alfredo
    Steinberg, Seth M.
    Alley, Michael C.
    Waud, William R.
    Bates, Susan E.
    Fojo, Tito
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (02) : 496 - 505
  • [5] The histone deacetylase inhibitor FK228 enhances adenoviral transgene expression by a transduction-independent mechanism
    Danielsson, Angelika
    Dzojic, Helena
    Cheng, Wing-Shing
    Essand, Magnus
    HUMAN GENE THERAPY, 2008, 19 (10) : 1105 - 1105
  • [6] Histone deacetylase inhibitor FK228 is a potent inducer of human fetal haemoglobin
    Cao, Hua
    Stamatoyannopoulos, George
    AMERICAN JOURNAL OF HEMATOLOGY, 2006, 81 (12) : 981 - 983
  • [7] Impact of novel histone deacetylase inhibitors, CHAP31 and FR901228 (FK228), on adenovirus-mediated transgene expression
    Taura, K
    Yamamoto, Y
    Nakajima, A
    Hata, K
    Uchinami, H
    Yonezawa, K
    Hatano, E
    Nishino, N
    Yamaoka, Y
    JOURNAL OF GENE MEDICINE, 2004, 6 (05): : 526 - 536
  • [8] FK228 increases adenovirus transgene expression and enhances adenovirus mediated suicide gene therapy in human bladder cancer cells
    Jian, WG
    Li, L
    Matsumoto, K
    Yu, J
    Davis, AR
    Lerner, SP
    MOLECULAR THERAPY, 2003, 7 (05) : S357 - S357
  • [9] The histone deacetylase inhibitor FK228 increases the efficacy of adenovirus-mediated p53 family gene therapy in in vitro and in vivo human cancer models
    Sasaki, Y
    Oshima, Y
    Mita, H
    Naishiro, Y
    Toyota, M
    Imai, K
    Tokino, T
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 231S - 231S
  • [10] Histone Deacetylase Inhibitor FK228 Enhances Adenovirus-mediated p53 Family Gene Therapy in Cancer Models
    Sasaki, Yasushi
    Idogawa, Masashi
    Suzuki, Hiromu
    Mita, Hiroaki
    Toyota, Minoru
    Shinomura, Yasuhisa
    Imai, Kohzoh
    Tokino, Takashi
    TUMOR BIOLOGY, 2008, 29 : 24 - 24
12345