共 29 条
Can transition to adult care for transplant recipients be improved by intensified services while patients are still in pediatrics?
被引:15
作者:
Annunziato, Rachel A.
[1
,2
]
Parbhakar, Meera
[1
]
Kapoor, Kathryn
[2
]
Matloff, Robyn
[3
,4
]
Casey, Nicole
[1
]
Benchimol, Corinne
[2
]
Hotchkiss, Hilary
[2
]
Nair, Vinay
[2
]
Saland, Jeffrey
[2
]
机构:
[1] Fordham Univ, Bronx, NY 10458 USA
[2] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[3] Westchester Cty Med Ctr, Valhalla, NY 10595 USA
[4] New York Med Coll, Valhalla, NY 10595 USA
关键词:
SOLID-ORGAN TRANSPLANTATION;
MEDICATION ADHERENCE;
HEALTH-CARE;
KIDNEY-TRANSPLANTATION;
GRAFT LOSS;
ADOLESCENT;
NONADHERENCE;
OUTCOMES;
RISK;
MANAGEMENT;
D O I:
10.7182/pit2015599
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
Context-Transferring out of pediatrics is a vulnerable time for transplant recipients. Use of a transition coordinator before and after transfer improves outcomes, although it is unclear whether placing a transition coordinator in pediatrics alone is beneficial. Objective-To determine if incorporating a transition coordinator in pediatrics only is associated with stable outcomes for kidney transplant recipients. Design-A retrospective chart review was conducted on outcomes for kidney transplant recipients who shifted service location between 2008 and 2012. Setting-A pediatric and adult transplant unit. Patients-Twenty-two patients transferred during the study period. Intervention-Twelve patients received more intensified preparation from the team's social worker, whose role was aligned with a transition coordinator position; 10 patients received standard care. Main Outcome Measures-The primary outcome was medication adherence, using a validated measure, standard deviations of tacrolimus blood levels. A standard deviation greater than 2.5 has been established as a threshold associated with poor outcomes such as rejection. Standard deviation of tacrolimus levels was compared for 1 year before and 1 year after transfer. Results-Medication adherence worsened from 1 year before (2.03 [SD, 0.75]) to 1 year after transfer (2.95 [SD, 1.38]; t = -3.07,P = .007). A repeated-measures analysis of variance indicated that this pattern was the same for patients who did and patients who did not receive intensified services in pediatrics (F-1,F-16 = 1.07, P = .32). (C) 2015 NATCO, The Organization for Transplant Professionals
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页码:236 / 242
页数:7
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