Synthesis of New Tetrazol-5-ylalkenyl Derivatives of Ferrocene by Wittig Olefination

被引：3

作者：

Grodner, Jacek ^{[1
]}

Salacinski, Tomasz ^{[1
]}

机构：

[1] Inst Ind Organ Chem, PL-03236 Warsaw, Poland

来源：

SYNTHESIS-STUTTGART | 2012年 / 44卷 / 19期

关键词：

iron; heterocycles; ylides; Wittig reactions; olefination; ferrocenes; BIOORGANOMETALLIC CHEMISTRY; COMPLEXES; RECEPTOR;

D O I：

10.1055/s-0032-1316736

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An effective and straightforward method has been developed for the synthesis of new olefinic derivatives of ferrocene that contain tetrazole rings. The method is based on condensation of 1-formyl-, 1,1'- diformyl-, or (E)-1-(2-formylvinyl) ferrocene with 1-substituted [(triphenylphosphoranylidene) methyl]-1H-tetrazoles, which are readily prepared by treatment of the corresponding phosphonium salts with aqueous sodium hydroxide. The olefination reaction proceeds in a diastereoselective manner with formation of the corresponding (E)-alkenes or (E,E)-dienes as the exclusive or major products.

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页码：3071 / 3076

页数：6

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