Cytokine modulators for allergic diseases

被引：20

作者：

Barnes, Peter J. ^{[1
]}

机构：

[1] Imperial Coll, Natl Heart & Lung Inst, London, England

来源：

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2001年 / 1卷 / 06期

关键词：

D O I：

10.1097/00130832-200112000-00011

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Cytokines play a critical role in orchestrating and perpetuating inflammation in allergic diseases and several specific cytokine inhibitors now in development for the treatment of asthma and other allergic diseases. The effects of inhibiting the T helper 2 cytokines interleukin-5, interleukin-13 and interleukin-9 are discussed, together with inhibition of tumor necrosis factor-alpha. Inhibitory cytokines, such as interleukin-10, interferons and interleukin-12, are also being considered in the treatment of allergic diseases. (C) 2001 Lippincott Williams & Wilkins.

引用

页码：555 / 560

页数：6

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