Fiber bundle endocytoscopy

被引：73

作者：

Hughes, Michael ^{[1
,2
]}

Chang, Tou Pin ^{[1
,3
]}

Yang, Guang-Zhong ^{[1
,2
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Hamlyn Ctr Robot Surg, London SW2 2AZ, England

[2] Imperial Coll London UK, Dept Comp, London, England

[3] Imperial Coll London UK, Dept Surg & Canc, London, England

来源：

BIOMEDICAL OPTICS EXPRESS | 2013年 / 4卷 / 12期

基金：

英国工程与自然科学研究理事会;

关键词：

CONFOCAL MICROSCOPY; 2-PHOTON MICROSCOPE; VIVO; ENDOMICROSCOPY; ESOPHAGUS; TECHNOLOGY;

D O I：

10.1364/BOE.4.002781

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Endocytoscopy is an optical biopsy technique which uses a miniaturized camera to capture white light microscopy images through an endoscope. We have developed an alternative design that instead relays images to an external camera via a coherent fiber bundle. In this paper we characterize the device and demonstrate microscopy of porcine tissue ex vivo. One advantage of our approach is the ease with which other bundle-compatible imaging modalities can be deployed simultaneously. We show this by acquiring quasi-simultaneous endocytoscopy and fluorescence confocal endomicroscopy images through a single fiber bundle. This opens up possibilities for multi-modal endomicroscopy, combining white light and fluorescence imaging. (C) 2013 Optical Society of America

引用

页码：2781 / 2794

页数：14

共 44 条

[21] Dark-field illuminated reflectance fiber bundle endoscopic microscope [J].

Liu, Xuan ;

Huang, Yong ;

Kang, Jin U. .

JOURNAL OF BIOMEDICAL OPTICS, 2011, 16 (04)

[22] Multispectral confocal microendoscope for in vivo and in situ imaging [J].

Makhlouf, Houssine ;

Gmitro, Arthur F. ;

Tanbakuchi, Anthony A. ;

Udovich, Josh A. ;

Rouse, Andrew R. .

JOURNAL OF BIOMEDICAL OPTICS, 2008, 13 (04)

[23] Recent advancement of observing living cells in the esophagus using CM double staining: Endocytoscopic atypia classification [J].

Minami, H. ;

Inoue, H. ;

Yokoyama, A. ;

Ikeda, H. ;

Satodate, H. ;

Hamatani, S. ;

Haji, A. ;

Kudo, S. .

DISEASES OF THE ESOPHAGUS, 2012, 25 (03) :235-241

[24] High-resolution imaging in Barrett's esophagus: a novel, low-cost endoscopic microscope [J].

Muldoon, Timothy J. ;

Anandasabapathy, Sharmila ;

Maru, Dipen ;

Richards-Kortum, Rebecca .

GASTROINTESTINAL ENDOSCOPY, 2008, 68 (04) :737-744

[25] Review article: in vivo imaging by endocytoscopy [J].

Neumann, H. ;

Fuchs, F. S. ;

Vieth, M. ;

Atreya, R. ;

Siebler, J. ;

Kiesslich, R. ;

Neurath, M. F. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2011, 33 (11) :1183-1193

[26]

NEUMANN H, 2012, GASTROINTEST ENDOS S, V75, P479

[27] In Vivo Diagnosis of Small-Cell Lung Cancer by Endocytoscopy [J].

Neumann, Helmut ;

Vieth, Michael ;

Neurath, Markus F. ;

Fuchs, Florian S. .

JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (06) :E131-E132

[28] Progress Toward Optical Biopsy: Bringing the Microscope to the Patient [J].

Newton, Richard C. ;

Kemp, Samuel V. ;

Shah, Pallav L. ;

Elson, Daniel ;

Darzi, Ara ;

Shibuya, Kiyoshi ;

Mulgrew, Stephen ;

Yang, Guang-Zhong .

LUNG, 2011, 189 (02) :111-119

[29] Endocytoscopy:: Novel endoscopic imaging technology for in-situ observation of bladder cancer cells [J].

Ohigashi, Takashi ;

Kozakai, Norihide ;

Mizuno, Ryuichi ;

Miyajima, Akira ;

Murai, Masaru .

JOURNAL OF ENDOUROLOGY, 2006, 20 (09) :698-701

[30]

Osdoit A., 2007, P SPIE, V6432, p64320F

← 1 2 3 4 5 →