Nitric Oxide Releasing Photoresponsive Nanohybrids As Excellent Therapeutic Agent for Cervical Cancer Cell Lines

被引：33
|
作者：
Sudhesh, Priya [1 ]
Tamilarasan, Kaviyarasan [1 ]
Arumugam, Palaniappan [1 ]
Berchmans, Sheela [1 ]
机构：
[1] CSIR Cent Electrochem Res Inst, Electrod & Electrocatalysis Div, Karaikkudi 630006, Tamil Nadu, India
来源：
ACS APPLIED MATERIALS & INTERFACES | 2013年 / 5卷 / 17期
关键词：
photoresponsive; nanohybrids; 2-mercapto-5-nitrobenzimidazole (MNBI); gold nanoparticles (GNP); nitric oxide (NO); apoptosis; NANOPARTICLES; FLUTAMIDE; SURFACE;
D O I：
10.1021/am402086m
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Gold nanoparticles (GNPs) that can release nitric oxide (NO) on visible-light irradiation were prepared using 2-mercapto-5-nitro benzimidazole (MNBI) as stabilizer. These nanoparticles meet overall prerequisites for biomedical applications like small sizes, water solubility, and stability. It was found that even a very low dosage of MNBI-stabilized GNPs exhibit appreciable tumor cell mortality against cervical cancer cell lines, demonstrating the role of NO in killing cancer cells.
引用
收藏
页码：8263 / 8266
页数：4
相关论文
共 50 条
  • [21] The effect of Lactobacillus casei extract on cervical cancer cell lines
    Kim, Soo-Nyung
    Lee, Won Moo
    Park, Kyoung Sik
    Kim, Jong Bin
    Han, Dae Jong
    Bae, Jaeman
    WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, 2015, 19 (04): : 306 - 312
  • [22] Toxicity assessment of magnesium oxide nano and microparticles on cancer and non-cancer cell lines
    Mangalampalli, Bhanuramya
    Dumala, Naresh
    Grover, Paramjit
    NUCLEUS-INDIA, 2019, 62 (03): : 227 - 241
  • [23] Toxicity assessment of magnesium oxide nano and microparticles on cancer and non-cancer cell lines
    Bhanuramya Mangalampalli
    Naresh Dumala
    Paramjit Grover
    The Nucleus, 2019, 62 : 227 - 241
  • [24] Inducing Immunogenic Cancer Cell Death through Oxygen-Economized Photodynamic Therapy with Nitric Oxide-Releasing Photosensitizers
    Xu, Feijie
    Wang, Meijun
    Dotse, Eunice
    Chow, Kwan T.
    Lo, Pui-Chi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 63 (37)
  • [25] Function of inducible nitric oxide synthase in the regulation of cervical cancer cell proliferation and the expression of vascular endothelial growth factor
    Dong, Jing
    Cheng, Mingjun
    Sun, Hong
    MOLECULAR MEDICINE REPORTS, 2014, 9 (02) : 583 - 589
  • [26] The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines
    Park, SW
    Lee, SG
    Song, SH
    Heo, DS
    Park, BJ
    Lee, DW
    Kim, KH
    Sung, MW
    INTERNATIONAL JOURNAL OF CANCER, 2003, 107 (05) : 729 - 738
  • [27] New Nitric Oxide-Releasing Compounds as Promising Anti-Bladder Cancer Drugs
    Varela, Maria
    Lopez, Miriam
    Ingold, Mariana
    Alem, Diego
    Perini, Valentina
    Perelmuter, Karen
    Bollati-Fogolin, Mariela
    Lopez, Gloria V.
    Hernandez, Paola
    BIOMEDICINES, 2023, 11 (01)
  • [28] WWOX induces apoptosis and inhibits proliferation in cervical cancer and cell lines
    Qu, Junjie
    Lu, Wen
    Li, Bilan
    Lu, Cong
    Wan, Xiaoping
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 31 (05) : 1139 - 1147
  • [29] Phytochemicals induce apoptosis by modulation of nitric oxide signaling pathway in cervical cancer cells
    Sundaram, M. K.
    Khan, M. A.
    Alalami, U.
    Somvanshi, P.
    Bhardwaj, T.
    Pramodh, S.
    Raina, R.
    Shekfeh, Z.
    Haque, S.
    Hussain, A.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2020, 24 (22) : 11827 - 11844
  • [30] The effect mechanism of Ginnalin A as a homeopathic agent on various cancer cell lines
    Vural , Hasibe
    OPEN CHEMISTRY, 2018, 16 (01): : 790 - 795
12345