Seasonal effects of Selank on the behavior of hibernating animals

被引：3
作者：
Semenova, TP [1 ]
Kozovskaya, MM
Zuikov, AV
Kozovskii, II
Andreeva, LA
机构：
[1] Russian Acad Sci, Inst Cell Biophys, Pushchino, Russia
[2] Russian Acad Sci, Inst Mol Genet, Moscow, Russia
[3] Russian Acad Med Sci, VV Zakusov Inst Pharmacol, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2005年 / 140卷 / 06期
基金：
俄罗斯基础研究基金会;
关键词：
Selank; exploratory behavior; stimulatory component of activity spectrum; hibernating animals; seasonal effects;
D O I：
10.1007/s10517-006-0060-0
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The test peptide had no effect on locomotor activity of animals. The selective stimulatory effect of Selank on exploratory behavior of hibernating animals was season-dependent. The maximum effect was observed under conditions of seasonal depression-like state.
引用
收藏
页码：705 / 707
页数：3
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