Seasonal effects of Selank on the behavior of hibernating animals

被引:3
作者
Semenova, TP [1 ]
Kozovskaya, MM
Zuikov, AV
Kozovskii, II
Andreeva, LA
机构
[1] Russian Acad Sci, Inst Cell Biophys, Pushchino, Russia
[2] Russian Acad Sci, Inst Mol Genet, Moscow, Russia
[3] Russian Acad Med Sci, VV Zakusov Inst Pharmacol, Moscow, Russia
基金
俄罗斯基础研究基金会;
关键词
Selank; exploratory behavior; stimulatory component of activity spectrum; hibernating animals; seasonal effects;
D O I
10.1007/s10517-006-0060-0
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The test peptide had no effect on locomotor activity of animals. The selective stimulatory effect of Selank on exploratory behavior of hibernating animals was season-dependent. The maximum effect was observed under conditions of seasonal depression-like state.
引用
收藏
页码:705 / 707
页数:3
相关论文
共 50 条
  • [1] Seasonal effects of Selank on the behavior of hibernating animals
    T. P. Semenova
    M. M. Kozlovskaya
    A. V. Zuikov
    I. I. Kozlovskii
    L. A. Andreeva
    Bulletin of Experimental Biology and Medicine, 2005, 140 : 705 - 707
  • [2] Functional Connectomic Approach to Studying Selank and Semax Effects
    Panikratova Y.R.
    Lebedeva I.S.
    Sokolov O.Y.
    Rumshiskaya A.D.
    Kupriyanov D.A.
    Kost N.V.
    Myasoedov N.F.
    Doklady Biological Sciences, 2020, 490 (1) : 9 - 11
  • [3] Selank and Short Peptides of the Tuftsin Family in the Regulation of Adaptive Behavior in Stress
    M. M. Kozlovskaya
    I. I. Kozlovskii
    E. A. Val'dman
    S. B. Seredenin
    Neuroscience and Behavioral Physiology, 2003, 33 (9) : 853 - 860
  • [4] A review of seasonal/circannual effects of laboratory rodent behavior
    Ferguson, Sherry A.
    Maier, Kaitlyn L.
    PHYSIOLOGY & BEHAVIOR, 2013, 119 : 130 - 136
  • [5] EXPLORATORY-BEHAVIOR AND LOCOMOTOR-ACTIVITY - A FAILURE TO FIND EFFECTS IN ANIMALS PRENATALLY EXPOSED TO COCAINE
    RILEY, EP
    FOSS, JA
    NEUROTOXICOLOGY AND TERATOLOGY, 1991, 13 (05) : 553 - 558
  • [6] Effects of Selank on Behavioral Reactions and Activities of Plasma Enkephalin-Degrading Enzymes in Mice with Different Phenotypes of Emotional and Stress Reactions
    O. Yu. Sokolov
    V. K. Meshavkin
    N. V. Kost
    A. A. Zozulya
    Bulletin of Experimental Biology and Medicine, 2002, 133 : 133 - 135
  • [7] Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions
    Sokolov, OY
    Meshavkin, VK
    Kost, NV
    Zozulya, AA
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2002, 133 (02) : 133 - 135
  • [8] Seasonal effects on the mechanisms of burn injuries
    Comcali, Bulent
    Ceylan, Cengiz
    Ozdemir, Buket Altun
    Ocakli, Serhat
    Ozel, Hikmet Pehlevan
    Yasti, Ahmet Cinar
    TURKISH JOURNAL OF SURGERY, 2022, 38 (01) : 5 - 10
  • [9] Common and Specific Effects of Selank, Noopept, and Semax on the Glycine Site of the NMDA Receptor in BALB/c and C57Bl/6 Mice Brains
    E. V. Vasil’eva
    A. A. Abdullina
    G. I. Kovalev
    Neurochemical Journal, 2023, 17 : 211 - 218
  • [10] Predominance of Nootropic or Anxiolytic Effects of Selank, Semax, and Noopept Peptides Depending on the Route of Administration to BALB/c and С57BL/6 Mice
    E. V. Vasileva
    E. A. Kondrakhin
    A. A. Abdullina
    R. M. Salimov
    G. I. Kovalev
    Neurochemical Journal, 2020, 14 : 268 - 278