CNVDetector: locating copy number variations using array CGH data

被引:10
作者
Chen, Peng-An [1 ]
Liu, Hsiao-Fei [1 ]
Chao, Kun-Mao [1 ,2 ,3 ]
机构
[1] Natl Taiwan Univ, Dept Comp Sci & Informat Engn, Taipei 10764, Taiwan
[2] Natl Taiwan Univ, Grad Inst Biomed Elect & Bioinformat, Taipei 10764, Taiwan
[3] Natl Taiwan Univ, Grad Inst Networking & Multimedia, Taipei 10764, Taiwan
关键词
D O I
10.1093/bioinformatics/btn517
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
CNVDetector is a program for locating copy number variations (CNVs) in a single genome. CNVDetector has several merits: (i) it can deal with the array comparative genomic hybridization data even if the noise is not normally distributed; (ii) it has a linear time kernel; (iii) its parameters can be easily selected; (iv) it evaluates the statistical significance for each CNV calling.
引用
收藏
页码:2773 / 2775
页数:3
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