Synthesis of 1,2,4-and 1,3,4-oxadiazoles from 1-aryl-5-methyl-1H-1,2,3-triazole-4-carbonyl chlorides

被引：30

作者：

Obushak, N. D. ^{[1
]}

Pokhodylo, N. T. ^{[1
]}

Pidlypnyi, N. I. ^{[1
]}

Matiichuk, V. S. ^{[1
]}

机构：

[1] Ivan Franko Lviv Natl Univ, UA-79005 Lvov, Ukraine

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 44卷 / 10期

关键词：

D O I：

10.1134/S1070428008100217

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Substituted 2-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)-1,3,4-oxadiazoles were synthesized by reaction of 1-aryl-5-methyl-1H-1,2,3-triazole-4-carbonyl chlorides with the corresponding 5-substituted 1H-tetrazoles. 5-Methyl-1-phenyl-1H-1,2,3-triazole-4-carbonyl chloride reacted with N'-hydroxybenzimidamides to give 3-aryl-5-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-1,2,4-oxadiazoles. Reactions of 4-(5-methyl-1H-1,2,3-triazol-1-yl)benzoic acid with N'-hydroxybenzimidamides resulted in the formation of 3-aryl-5-[4-(5-methyl-1H-1,2,3-triazol-1-yl)phenyl]-1,2,4-oxadiazoles.

引用

页码：1522 / 1527

页数：6

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