Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection

被引：105
作者：
Polyak, Stephen J. [1 ,2 ,3 ]
Ferenci, Peter [4 ]
Pawlotsky, Jean-Michel [5 ,6 ]
机构：
[1] Univ Washington, Dept Lab Med, Seattle, WA 98195 USA
[2] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
[3] Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA
[4] Med Univ Vienna, Vienna, Austria
[5] Univ Paris Est, Henri Mondor Hosp, Dept Virol, Natl Reference Ctr Viral Hepatitis B C & Delta, Creteil, France
[6] Hop Henri Mondor, INSERM, U955, F-94010 Creteil, France
来源：
HEPATOLOGY | 2013年 / 57卷 / 03期
关键词：
FATTY LIVER-DISEASE; INTRAVENOUS SILIBININ MONOTHERAPY; LONG-TERM TREATMENT; MILK THISTLE; DOUBLE-BLIND; SILYBUM-MARIANUM; PROSTATE-CANCER; PHASE-I; LIPID-PEROXIDATION; RESCUE TREATMENT;
D O I：
10.1002/hep.26179
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：1262 / 1271
页数：10
相关论文
共 79 条
[21]   Silymarin use and liver disease progression in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial [J].
Freedman, N. D. ;
Curto, T. M. ;
Morishima, C. ;
Seeff, L. B. ;
Goodman, Z. D. ;
Wright, E. C. ;
Sinha, R. ;
Everhart, J. E. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2011, 33 (01) :127-137
[22]   Effect of Silymarin (Milk Thistle) on Liver Disease in Patients With Chronic Hepatitis C Unsuccessfully Treated With Interferon Therapy A Randomized Controlled Trial [J].
Fried, Michael W. ;
Navarro, Victor J. ;
Afdhal, Nezam ;
Belle, Steven H. ;
Wahed, Abdus S. ;
Hawke, Roy L. ;
Doo, Edward ;
Meyers, Catherine M. ;
Reddy, K. Rajender .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 308 (03) :274-282
[23]  
GATTI G, 1994, INT J CLIN PHARM TH, V32, P614
[24]   Silybin and silymarin -: New and emerging applications in medicine [J].
Gazak, Radek ;
Walterova, Daniela ;
Kren, Vladimir .
CURRENT MEDICINAL CHEMISTRY, 2007, 14 (03) :315-338
[25]   Effects of Silybum marianum on serum hepatitis C virus RNA, alanine aminotransferase levels and well-being in patients with chronic hepatitis C [J].
Gordon, A ;
Hobbs, DA ;
Bowden, DS ;
Bailey, MJ ;
Mitchell, J ;
Francis, AJP ;
Roberts, SK .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2006, 21 (01) :275-280
[26]   Silymarin Ascending Multiple Oral Dosing Phase I Study in Noncirrhotic Patients With Chronic Hepatitis C [J].
Hawke, Roy L. ;
Schrieber, Sarah J. ;
Soule, Tedi A. ;
Wen, Zhiming ;
Smith, Philip C. ;
Reddy, K. Rajender ;
Wahed, Abdus S. ;
Belle, Steven H. ;
Afdhal, Nezam H. ;
Navarro, Victor J. ;
Berman, Josh ;
Liu, Qi-Ying ;
Doo, Edward ;
Fried, Michael W. .
JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 50 (04) :434-449
[27]  
Huber R, 2005, EUR J MED RES, V10, P68
[28]  
KIESEWETTER E, 1977, LEBER MAGEN DARM, V7, P318
[29]   AMANITA POISONING - TREATMENT AND THE ROLE OF LIVER-TRANSPLANTATION [J].
KLEIN, AS ;
HART, J ;
BREMS, JJ ;
GOLDSTEIN, L ;
LEWIN, K ;
BUSUTTIL, RW .
AMERICAN JOURNAL OF MEDICINE, 1989, 86 (02) :187-193
[30]  
Koller F., 2011, INTERACTION SILIBINI
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