Retinal vessel changes after laser treatment for retinopathy of prematurity

被引：8

作者：

Kwon, Julie Y. ^{[1
,2
]}

Ghodasra, Devon H. ^{[3
]}

Karp, Karen A. ^{[1
]}

Ying, Gui-shuang ^{[3
]}

Wilson, Clare M. ^{[4
]}

Huang, Jiayan ^{[3
]}

Mills, Monte D. ^{[1
,3
]}

Fielder, Alistair R. ^{[5
]}

Quinn, Graham E. ^{[1
,3
]}

机构：

[1] Childrens Hosp Philadelphia, Div Ophthalmol, Philadelphia, PA 19104 USA

[2] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Camden, NJ 08103 USA

[3] Univ Penn, Scheie Eye Inst, Philadelphia, PA 19104 USA

[4] UCL Inst Ophthalmol, London, England

[5] City Univ London, London, England

来源：

JOURNAL OF AAPOS | 2012年 / 16卷 / 04期

关键词：

IMAGE-ANALYSIS; DISEASE; PHOTOCOAGULATION; TORTUOSITY; WIDTH;

D O I：

10.1016/j.jaapos.2012.04.002

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

BACKGROUND The clinical response to retinopathy of prematurity (ROP) treatment is currently assessed subjectively. This study aims to quantify treatment response objectively by assessing changes in digital images of posterior pole retinal vessel width and tortuosity. METHODS Images of 30 right eyes with type 1 ROP obtained at up to three time points were analyzed: before treatment (T = 0) and 1 (T = 1) and/or 2 weeks (T = 2) after treatment. Width and tortuosity of retinal vessels were analyzed from digital images using computer-assisted image analysis software. RESULTS Vessel width decreased by 20% (P < 0.004) within the first week and remained stable by the second week after laser treatment. Vessel tortuosity did not significantly change by the first week but decreased 27% (P < 0.01) by second week. CONCLUSIONS Vessel width appears to decrease dramatic within the first week, whereas the regression of tortuosity follows a slower course. (J AAPOS 2012;16:350-353)

引用

页码：350 / 353

页数：4

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