The role of amino acids in nisin and pediocin production by two lactic acid bacteria -: A factorial study

被引：38

作者：

Vázquez, JA ^{[1
]}

Cabo, ML ^{[1
]}

González, MP ^{[1
]}

Murado, MA ^{[1
]}

机构：

[1] CSIC, Inst Invest Marinas, Galicia 36208, Spain

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 2004年 / 34卷 / 3-4期

关键词：

amino acids; nisin production; pediocin production; factorial study;

D O I：

10.1016/j.enzmictec.2003.11.005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In conventional and repeatedly re-alkalized cultures of two lactic acid bacteria, the effects of five amino acids and their interactions on biomass and bacteriocin (nisin and pediocin) production were studied. Nisin production was stimulated by cysteine and tryptophan, and depressed by proline. Equations describing biomass production in Lactococcus lactis, and biomass and pediocin productions in Pediococcus acidilactici, contain numerous terms with three and four variables, indicating that none of the amino acids seems to play a relevant individual role. Stimulation due to the pH-stepwise profiles exceed significantly those of the most effective amino acid combinations and promote much faster consumption of some amino acids. Since a pH-stepwise Culture can be considered as a series of successive incubations, each starting up in presence of the metabolic products from the preceding step, these results are more compatible with an auto-stimulatory mechanism rather than a nutritional phenomenon. (C) 2003 Elsevier Inc. All rights reserved.

引用

页码：319 / 325

页数：7

共 26 条

[1] Influence of complex nutrients, temperature and pH on bacteriocin production by Lactobacillus sakei CCUG 42687 [J].