Recent Progress Towards the Identification of Inhibitors of Mycobacterial Cell Wall Polysaccharide Biosynthesis

被引：46

作者：

Lowary, Todd L. ^{[1
]}

机构：

[1] Ohio State Univ, Dept Chem, 100 West 18th Ave, Columbus, OH 43210 USA

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2003年 / 3卷 / 07期

基金：

美国国家卫生研究院;

关键词：

Tuberculsosis; mycobacteria; polysaccharides; furanosides; bacterial cell wall; inhibitors;

D O I：

10.2174/1389557033487683

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Mycobacterial infections have recently attracted significant attention from international health agencies due to the resurgence of these diseases worldwide. This review summarizes the recent work directed towards the identification of new anti-tuberculosis agents that act by inhibiting mycobacterial cell wall polysaccharide biosynthesis.

引用

页码：689 / 702

页数：14

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