Advances in Amblyopia: What Have We Learned From PEDIG Trials?

被引:53
作者
Gunton, Kammi B. [1 ]
机构
[1] Wills Eye Inst, Dept Pediat Ophthalmol, Philadelphia, PA 19107 USA
关键词
amblyopia; treatment; patching; atropine; PEDIG; anisometropia; CHILDREN AGED 7; RANDOMIZED-TRIAL; MODERATE AMBLYOPIA; ANISOMETROPIC AMBLYOPIA; REFRACTIVE AMBLYOPIA; READING PERFORMANCE; VISUAL-ACUITY; FOLLOW-UP; ATROPINE; CESSATION;
D O I
10.1542/peds.2012-1622
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Amblyopia is the most common cause of preventable visual loss in children. This article reviews treatment options, durations, and efficacy in randomized multicentered trials conducted by the Pediatric Eye Disease and Investigator Group in the last decade. Parents and patients should be counseled that many forms of treatment are efficacious, allowing the option of choice of best-tolerated treatment method. Compliance is key to successful treatment. The course of treatment is likely at least 6-12 months, with yearly follow-up suggested once amblyopia has been treated to monitor for regression. Pediatrics 2013;131:540-547
引用
收藏
页码:540 / 547
页数:8
相关论文
共 41 条
[1]   A randomized controlled trial of unilateral strabismic and mixed amblyopia using occlusion dose monitors to record compliance [J].
Awan, M ;
Proudlock, FA ;
Gottlob, I .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2005, 46 (04) :1435-1439
[2]   A randomized trial of prescribed patching regimens for treatment of severe amblyopia in children [J].
Beck, RW .
OPHTHALMOLOGY, 2003, 110 (11) :2075-2087
[3]   The amblyopia treatment index [J].
Cole, SR ;
Beck, RW ;
Moke, PS ;
Celano, MP ;
Drews, CD ;
Repka, MX ;
Holmes, JM ;
Birch, EE ;
Kraker, RT ;
Kip, KE .
JOURNAL OF AAPOS, 2001, 5 (04) :250-254
[4]   The course of moderate amblyopia treated with atropine in children: Experience of the amblyopia treatment study [J].
Cotter, S ;
Astle, WF ;
Beck, RW ;
Birch, EE ;
Chandler, DL ;
Davitt, BV ;
Holmes, JM ;
Kraker, RT ;
Miller, MM ;
Repka, MX ;
Saunders, RA ;
Wallace, DK .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2003, 136 (04) :630-639
[5]   Treatment of strabismic amblyopia with refractive correction [J].
Cotter, Susan A. ;
Edwards, Allison R. ;
Arnold, Robert W. ;
Astle, William F. ;
Barnhardt, Carmen N. ;
Beck, Roy W. ;
Birch, Eileen E. ;
Donahue, Sean P. ;
Everett, Donald F. ;
Felius, Joost ;
Holmes, Jonathan M. ;
Kraker, Raymond T. ;
Melia, B. Michele ;
Repka, Michael X. ;
Wallace, David K. ;
Weise, Katherine K. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2007, 143 (06) :1060-1063
[6]   Treatment of anisometropic amblyopia in children with refractive correction [J].
Cotter, Susan A. ;
Edwards, Allison R. ;
Wallace, David K. ;
Beck, Roy W. ;
Arnold, Robert W. ;
Astle, William F. ;
Barnhardt, Carmen N. ;
Birch, Eileen E. ;
Donahue, Sean P. ;
Everett, Donald F. ;
Felius, Joost ;
Holmes, Jonathan M. ;
Kraker, Raymond T. ;
Melia, B. Michele ;
Repka, Michael X. ;
Sala, Nicholas A. ;
Silbert, David I. ;
Weise, Katherine K. .
OPHTHALMOLOGY, 2006, 113 (06) :895-903
[7]  
Cotter SA, 2009, ARCH OPHTHALMOL-CHIC, V127, P22, DOI 10.1001/archophthalmol.2008.520
[8]   Evaluating the burden of amblyopia treatment from the parent and child's perspective [J].
Felius, Joost ;
Chandler, Danielle L. ;
Holmes, Jonathan M. ;
Chu, Raymond H. ;
Cole, Stephen R. ;
Hill, Michael ;
Huang, Kristine ;
Kulp, Marjean Taylor ;
Lazar, Elizabeth L. ;
Matta, Noelle S. ;
Melia, Michele ;
Wallace, David K. .
JOURNAL OF AAPOS, 2010, 14 (05) :389-395
[9]  
Glaser SR, 2002, ARCH OPHTHALMOL-CHIC, V120, P268
[10]   The role of compliance in 2 vs 6 hours of patching in children with amblyopia [J].
Gottlob, I ;
Awan, M ;
Proudlock, F .
ARCHIVES OF OPHTHALMOLOGY, 2004, 122 (03) :422-423