Successful Treatment of Refractory Immune Thrombocytopenia With Rituximab in a 10-Week-Old Infant

被引：1

作者：

Gray, Charmaine ^{[1
]}

Kalumba, Kongolo ^{[2
]}

Pati, Nalini ^{[2
]}

Peterson, Anna ^{[1
]}

Connell, Tom G. ^{[1
,3
]}

机构：

[1] Royal Childrens Hosp Melbourne, Murdoch Childrens Res Inst, Dept Gen Med, Parkville, Vic 3052, Australia

[2] Royal Childrens Hosp Melbourne, Murdoch Childrens Res Inst, Dept Haematol, Parkville, Vic 3052, Australia

[3] Royal Childrens Hosp Melbourne, Murdoch Childrens Res Inst, Infect Dis Unit, Parkville, Vic 3052, Australia

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2013年 / 35卷 / 04期

关键词：

immune; thrombocytopenia; purpura; rituximab; FOLLOW-UP; CHILDREN; MANAGEMENT; CHILDHOOD; THERAPY;

D O I：

10.1097/MPH.0b013e31828308be

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Immune thrombocytopenic purpura (ITP) that is unresponsive to conventional treatment is uncommon. In this situation, additional therapeutic options are limited and management is challenging. We describe the case of a 10-week-old infant that developed life-threatening ITP that was unresponsive to immunoglobulin and corticosteroids that was successfully managed with the monoclonal antibody rituximab. The literature on the use of rituximab in nonresponsive ITP is reviewed.

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收藏

页码：E174 / E177

页数：4

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