Increased activation of HDAC1, 2, and 6, and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma

被引：1
作者：
Chuang, Jian-Ying [1 ]
Yang, Wen-Bin [1 ]
Hsu, Che-Chia [1 ]
机构：
[1] Taipei Med Univ, Taipei, Taiwan
来源：
FASEB JOURNAL | 2020年 / 34卷
关键词：
D O I：
10.1096/fasebj.2020.34.s1.02838
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [31] The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter
    Xie, RL
    Gupta, S
    Miele, A
    Shiffman, D
    Stein, JL
    Stein, GS
    van Wijnen, AJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (29) : 26589 - 26596
  • [32] TRIM5α recruits HDAC1 to p50 and Sp1 and promotes H3K9 deacetylation at the HIV-1 LTR
    Ran, Xiang-Hong
    Zhu, Jia-Wu
    Ni, Run-Ze
    Zheng, Yong-Tang
    Chen, Ya-Yun
    Zheng, Wei-Hua
    Mu, Dan
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [33] Prefoldin proteins 2/6, and HMG20B are regulated by HDAC1, HDAC3 and are novel therapeutic and prognostic biomarkers in hepatocellular carcinoma
    Aldughaim, Mohammed S.
    Alshehri, Mana M.
    Al-yhya, Nouf
    Wadaan, Mohammad Ahmed
    Al-ghamdi, Saleh
    Habibullah, Mahmoud M.
    Alothaid, Hani
    Khan, Muhammad Farooq
    JOURNAL OF KING SAUD UNIVERSITY SCIENCE, 2022, 34 (02)
  • [34] REGULATION OF HETEROCHROMATIN FORMATION AND TUMOR SUPPRESSION IN LEUKEMIA BY IKAROS, HDAC1 AND EZH2
    Ding, Y.
    He, B.
    Schramm, J. W.
    Bogush, D.
    Desai, D.
    Sharma, A.
    Dovat, S.
    ANNALS OF HEMATOLOGY, 2023, 102 (SUPPL 1) : S29 - S30
  • [35] Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiornyocytes
    Seyed, Mahdie
    DiMano, Joseph X.
    GENE, 2007, 400 (1-2) : 150 - 157
  • [36] Hypoxic activation of FVII gene in cancer cells mediated by interaction among HIF2α, Sp1, and HDAC4
    Koizume, Shiro
    Miyagi, Etsuko
    Hirahara, Fumiki
    Nakamura, Yoshiyasu
    Takano, Yasuo
    Ruf, Wolfram
    Miyagi, Yohei
    CANCER RESEARCH, 2011, 71
  • [37] Porcine Epidemic Diarrhea Virus Inhibits HDAC1 Expression To Facilitate Its Replication via Binding of Its Nucleocapsid Protein to Host Transcription Factor Sp1
    Xu, Jidong
    Mao, Junyong
    Han, Xiao
    Shi, Fushan
    Gao, Qin
    Wang, Tingjun
    Zhang, Zhenning
    Shan, Ying
    Fang, Weihuan
    Li, Xiaoliang
    JOURNAL OF VIROLOGY, 2021, 95 (18)
  • [38] Sp1 binding is critical for promoter assembly and activation of the MCP-1 gene by tumor necrosis factor
    Ping, DS
    Boekhoudt, G
    Zhang, FP
    Morris, A
    Philipsen, S
    Warren, ST
    Boss, JM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (03) : 1708 - 1714
  • [39] Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice
    Xie, Yonggang
    Li, Zhen
    Xu, Hongyu
    Ma, Jiahai
    Li, Tao
    Shi, Cunxian
    Jin, Jin
    ACS CHEMICAL NEUROSCIENCE, 2022, 13 (09): : 1446 - 1455
  • [40] Selective inhibition of HDAC1 and HDAC2 counteracts medulloblastoma cell growth in mouse models through Gli acetylation
    Coni, S.
    Mancuso, A. B.
    Di Magno, L.
    Sdruscia, G.
    Rotili, D.
    Mai, A.
    Canettieri, G.
    EUROPEAN JOURNAL OF CANCER, 2016, 61 : S143 - S144
12345