Sinusoidal endothelial cells are damaged and display enhanced autophagy in myelodysplastic syndromes

被引:6
作者
Houwerzijl, Ewout J. [1 ]
van den Heuvel, Fiona A. J. [2 ,3 ]
Blom, Nel R. [2 ,3 ]
van der Want, Johannes J. L. [4 ]
Mulder, Andre B. [3 ]
Vellenga, Edo [2 ]
机构
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Vasc Med, NL-9713 AV Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Haematol, NL-9713 AV Groningen, Netherlands
[3] Univ Groningen, Univ Med Ctr Groningen, NL-9713 AV Groningen, Netherlands
[4] Univ Groningen, Univ Med Ctr Groningen, Dept Cell Biol, NL-9713 AV Groningen, Netherlands
关键词
MDS; endothelial cells; electron microscopy; HUMAN BONE-MARROW;
D O I
10.1111/bjh.12227
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:443 / 446
页数:4
相关论文
共 10 条
  • [1] Ontogenic emergence of the hematon, a morphogenetic stromal unit that supports multipotential hematopoietic progenitors in mouse bone marrow
    Blazsek, I
    Chagraoui, J
    Péault, B
    [J]. BLOOD, 2000, 96 (12) : 3763 - 3771
  • [2] Immunophenotypic, cytogenetic and functional characterization of circulating endothelial cells in myelodysplastic syndromes
    Della Porta, M. G.
    Malcovati, L.
    Rigolin, G. M.
    Rosti, V.
    Bonetti, E.
    Travaglino, E.
    Boveri, E.
    Galli, A.
    Boggi, S.
    Ciccone, M.
    Pramparo, T.
    Mazzini, G.
    Invernizzi, R.
    Lazzarino, M.
    Cazzola, M.
    [J]. LEUKEMIA, 2008, 22 (03) : 530 - 537
  • [3] The vascular niche: home for normal and malignant hematopoietic stem cells
    Doan, P. L.
    Chute, J. P.
    [J]. LEUKEMIA, 2012, 26 (01) : 54 - 62
  • [4] Erythroid precursors from patients with low-risk myelodysplasia demonstrate ultrastructural features of enhanced autophagy of mitochondria
    Houwerzijl, E. J.
    Pol, H-W D.
    Blom, N. R.
    van der Want, J. J. L.
    de Wolf, J. Thm
    Vellenga, E.
    [J]. LEUKEMIA, 2009, 23 (05) : 886 - 891
  • [5] The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage
    Lancrin, Christophe
    Sroczynska, Patrycja
    Stephenson, Catherine
    Allen, Terry
    Kouskoff, Valerie
    Lacaud, Georges
    [J]. NATURE, 2009, 457 (7231) : 892 - 895
  • [6] Basic and Therapeutic Aspects of Angiogenesis
    Potente, Michael
    Gerhardt, Holger
    Carmeliet, Peter
    [J]. CELL, 2011, 146 (06) : 873 - 887
  • [7] Differentiation and expansion of endothelial cells from human bone marrow CD133+ cells
    Quirici, N
    Soligo, D
    Caneva, L
    Servida, F
    Bossolasco, P
    Deliliers, GL
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2001, 115 (01) : 186 - 194
  • [8] Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo
    Salter, Alice B.
    Meadows, Sarah K.
    Muramoto, Garrett G.
    Himburg, Heather
    Doan, Phuong
    Daher, Pamela
    Russell, Lauren
    Chen, Benny
    Chao, Nelson J.
    Chute, John P.
    [J]. BLOOD, 2009, 113 (09) : 2104 - 2107
  • [9] MARROW-BLOOD BARRIER
    TAVASSOLI, M
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1979, 41 (03) : 297 - 302
  • [10] WICKRAMASINGHE SN, 1991, CLIN LAB HAEMATOL, V13, P263